Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease

Pagan Fernando L.; Wilmarth Barbara; Torres-Yaghi Yasar; Hebron Michaeline L.; Mulki Sanjana; Ferrante Dalila; Matar Sara; Ahn Jaeil; Moussa Charbel

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Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease

机译：Nilotinib在帕金森病中的长期安全性和临床影响

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Background Nilotinib is US Food and Drug Administration-approved for leukemia, and this open-label study investigated the safety, tolerability, and potential clinical effects of nilotinib in medically optimized patients with Parkinson's disease.

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《Movement disorders》 |2021年第3期|共10页
作者
Pagan Fernando L.; Wilmarth Barbara; Torres-Yaghi Yasar; Hebron Michaeline L.; Mulki Sanjana; Ferrante Dalila; Matar Sara; Ahn Jaeil; Moussa Charbel;
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作者单位

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

Georgetown Univ Med Ctr Dept Biostat Bioinformat &

Biomath Washington DC 20007 USA;

Georgetown Univ Med Ctr Dept Neurol Translat Neurotherapeut Program Lab Dementia &

Pa;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Nilotinib; Parkinsonamp; apos; s disease; UPDRS; PDQamp; 8208; 39; MoCA;

机译：nilotinib;帕金森＆amp;疾病;updrs;pdq＆amp;8208;39;moca;
入库时间 2022-08-20 18:28:00

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3. Long-term Levodopa Treatment Accelerates the Circadian Rhythm Dysfunction in a 6-hydroxydopamine Rat Model of Parkinson's Disease [J] . Si-Yue Li, Ya-Li Wang, Wen-Wen Liu, 中华医学杂志（英文版） . 2017,第009期
4. Long-term Efficacy of Subthalamic Nucleus Deep Brain Stimulation in Parkinson's Disease: A 5-year Follow-up Study in China [J] . Lu-Lu Jiang, Jin-Long Liu, Xiao-Li Fu, 中华医学杂志（英文版） . 2015,第018期
5. Nilotinib Effects on Safety, Tolerability, and Potential Biomarkers in Parkinson Disease A Phase 2 Randomized Clinical Trial [J] . Pagan Fernando. L., Hebron Michaeline L., Wilmarth Barbara, JAMA neurology . 2020,第3期

机译：Nilotinib对帕金森病的安全性，耐受性和潜在的生物标志物效应了帕金森病的2期随机临床试验
6. A long-term follow-up of safety and clinical efficacy of NTCELL (R) [Immunoprotected (Alginate-encapsulated) porcine choroid plexus cells for xenotransplantation] in patients with Parkinson's disease [J] . Mulroy Eoin, Snow Barry, Bok Arnold, Parkinsonism & related disorders . 2021,第1期

机译：NTCell（R）的安全性和临床疗效的长期随访[免疫保护（藻酸盐包封的）猪脉络膜丛细胞在帕金森病的患者中
7. Brain Networks Underlying the Clinical Effects of Long-Term Subthalamic Stimulation for Parkinson's Disease: A 4-Year Follow-up Study with rCBF SPECT. [J] . Sestini S, Ramat S, Formiconi AR, The Journal of Nuclear Medicine . 2005,第9期

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8. A wearable system for long-term ubiquitous monitoring of common motor symptoms in patients with Parkinson#039;s disease [C] . Tsipouras Markos G, Tzallas Alexandros T., Karvounis Evaggelos C., IEEE-EMBS International Conference on Biomedical and Health Informatics . 2014

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9. Role of the prolyl isomerase Pin1 in the pathogenesis of Parkinson's disease and neuroprotection by novel targeted compounds in pre-clinical animal models of the disease [D] . Ghosh, Anamitra 2012

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11. Long‐Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease [O] . Fernando L. Pagan, Barbara Wilmarth, Yasar Torres‐Yaghi, 2020

机译：Nilotinib在帕金森病中的长期安全性和临床影响
12. Statistical Power of Studies Examining the Cognitive Effects of Subthalamic Nucleaus Deep Brain Stimulation in Parkinson's Disease. [R] . Woods, S. P., Rippeth, J. D., Conover, E., 2006

机译：研究统计学研究对丘脑底核深部脑刺激对帕金森病的认知影响。

Long-Term Safety and Clinical Effects of Nilotinib in Parkinson's Disease

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