RADIOCONTRAST-INDUCED ANAPHYLAXIS DESPITE PRETREATMENT AND USE OF ISO-OSMOLAR CONTRAST

摘要

Patients may experience anaphylactic reactions with intravascu-lar and nonvascular exposure to radiocontrast media (RCM). Patients who have had anaphylactic reactions to RCM are at increased risk to have repeat reactions on subsequent exposure. The mechanism responsible for RCM-induced anaphylactic reactions is unknown. Because use of low-osmolar contrast media has been associated with a decrease in the incidence of RCM-induced anaphylaxis, it has been proposed that these reactions are triggered by hyperosmolarity