Assessment and clinical interpretation of reduced IgG values.

摘要

Patients are often referred to immunologists for the evaluation of reduced serum IgG levels. Because antibody deficiencies are the most common of the primary immune defects, examination of humoral immunity in these patients is valuable.1-2 This article is the first in a series dealing with the diagnosis of immunodeficiency disorders, with focus on the interpretation of reduced IgG values. The information presented should be interpreted in the clinical context of each patient along with other evaluation measures, such as IgM and IgA levels and functional humoral immunity, discussed in subsequent articles.