PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer

Rischin Danny; Gil-Martin Marta; Gonzalez-Martin Antonio; Brana Irene; Hou June Y.; Cho Daniel; Falchook Gerald S.; Formenti Silvia; Jabbour Salma; Moore Kathleen; Naing Aung; Papadopoulos Kyriakos P.; Baranda Joaquina; Fury Wen; Feng Minjie; Stankevich Elizabeth; Li Jingjin; Yama-Dang N. Alice; Yoo Suk-Young; Lowy Israel; Mathias Melissa; Fury Matthew G.

首页> 外文期刊>Gynecologic Oncology: An International Journal >PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer

【24h】

PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer

机译：复发性或转移性宫颈癌的PD-1阻断：来自Cemiplimab期I的数据扩张队列和宫颈癌PD-L1表达的表征

获取原文

获取原文并翻译 | 示例

获取外文期刊封面目录资料

开具论文收录证明 >>

文献代查 >>

文献数据库（团队版） >>

页面导航

摘要
著录项
引文网络
相似文献
相关主题

摘要

Objectives. To characterize the safety, tolerability, and anti-tumor activity of cemiplimab asmonotherapy or in combination with hypofractionated radiation therapy (hfRT) in patients with recurrent or metastatic cervical cancer. To determine the association between histology and programmed death-ligand 1 (PD-L1) expression.

机译：None

著录项

来源
《Gynecologic Oncology: An International Journal》 |2020年第2期|共7页
作者
Rischin Danny; Gil-Martin Marta; Gonzalez-Martin Antonio; Brana Irene; Hou June Y.; Cho Daniel; Falchook Gerald S.; Formenti Silvia; Jabbour Salma; Moore Kathleen; Naing Aung; Papadopoulos Kyriakos P.; Baranda Joaquina; Fury Wen; Feng Minjie; Stankevich Elizabeth; Li Jingjin; Yama-Dang N. Alice; Yoo Suk-Young; Lowy Israel; Mathias Melissa; Fury Matthew G.;
展开▼
作者单位

Peter MacCallum Canc Ctr Dept Med Oncol 305 Grattan St Melbourne Vic 3000 Australia;

Inst Catala Oncol IDIBELL Barcelona Spain;

Clin Univ Navarra Madrid Spain;

Vali dHebron Univ Hosp Vali dHebron Inst Oncol VHIO Med Oncol Dept Barcelona Spain;

Columbia Univ Div Gynecol Oncol Med Ctr New York NY USA;

NYU Langone Med Ctr Perlmutter Canc Ctr New York NY USA;

HealthONE Sarah Cannon Res Inst Denver CO USA;

Weill Cornell Med Dept Radiat Oncol New York NY USA;

Rutgers Canc Inst New Jersey Dept Radiat Oncol New Brunswick NJ USA;

Univ Oklahoma Hlth Sci Ctr Sarah Cannon Res Inst Stephenson Canc Ctr Oklahoma City OK USA;

Univ Texas MD Anderson Canc Ctr Dept Invest Canc Therapeut Phase 1 Clin Trials Program Houston;

START San Antonio TX USA;

Univ Kansas Canc Ctr Early Phase Pmgram Clin Res Ctr Fairway KS USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

Regeneron Pharmaceut Inc Basking Ridge NJ USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

Regeneron Pharmaceut Inc Basking Ridge NJ USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

Regeneron Pharmaceut Inc Basking Ridge NJ USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

Regeneron Pharmaceut Inc 777 Old Saw Mill River Rd Tarrytown NY 10591 USA;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
Cemiplimab; Recurrent cervical cancer; Metastatic cervical cancer; Anti-PD-1;

机译：cemiplimab;复发性宫颈癌;转移性宫颈癌;反PD-1;

相似文献

外文文献
中文文献
专利

1. The correlation of p16 and MMPs expression in cervical secretions with the angiogenesis and cell proliferation in cervical cancer tissue [J] . Lai-Fang Zhu 海南医科大学学报（英文版） . 2017,第008期
2. The correlation of p16 and MMPs expression in cervical secretions with the angiogenesis and cell proliferation in cervical cancer tissue [J] . Lai-Fang Zhu 海南医科大学学报(英文版) . 2017,第008期
3. Tolerability and antitumor activity of cemiplimab, a human monoclonal anti?PD-1, as monotherapy in patients with pretreated non-small cell lung cancer (NSCLC): Data from the Phase 1 NSCLC expansion cohort [J] . Moreno Victor, Garrido Pilar, Papadopoulos Kyriakos P., Lung cancer: Journal of the International Association for the Study of Lung Cancer . 2021,第1期

机译：CeMiplimab的耐受性和抗肿瘤活性，一种人单克隆抗βPD-1，作为预处理非小细胞肺癌（NSCLC）患者的单一疗法：来自第1阶段NSCLC扩展队列的数据
4. The Roles of Programmed Cell Death Ligand-1/ Programmed Cell Death-1 (PD-L1/PD-1) in HPV-induced Cervical Cancer and Potential for their Use in Blockade Therapy [J] . Zhang Lifang, Zhao Yu, Tu Quanmei, Current medicinal chemistry . 2021,第5期

机译：编程的细胞死亡配体-1 /编程细胞死亡-1（PD-L1 / PD-1）在HPV诱导的宫颈癌中的作用以及它们在阻滞疗法中使用的潜力
5. Immune checkpoint expression on peripheral cytotoxic lymphocytes in cervical cancer patients: moving beyond the PD-1/PD-L1 axis [J] . Solorzano-Ibarra F., Alejandre-Gonzalez A. G., Ortiz-Lazareno P. C., Clinical and Experimental Immunology: An Official Journal of the British Society for Immunology . 2021,第1期

机译：宫颈癌患者外周细胞毒性淋巴细胞的免疫检查点表达：超越PD-1 / PD-L1轴
6. Clinical role of hWAPL in histologic diagnosis of cervical cancer and cervical intraepithelial neoplasia: Correlation with p16INK4a expression and HPV testing [C] . Xie Yonghong, Shen Peng, Chen Linlong, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：hWAPL在宫颈癌和宫颈上皮内瘤变的组织学诊断中的临床作用：与p16INK4a表达和HPV检测的相关性
7. Knowledge, attitudes, and beliefs regarding cervical cancer and screening and perceived barriers to cervical cancer screening programs among Thai immigrant women living in Germany. [D] . Ice, Unchalee Vatanasook. 2012

机译：在德国居住的泰国移民妇女中有关宫颈癌和筛查的知识，态度和信念以及对宫颈癌筛查计划的认知障碍。
8. PRIMMO study protocol: a phase II study combining PD-1 blockade radiation and immunomodulation to tackle cervical and uterine cancer [O] . Sandra Tuyaerts, An M. T. Van Nuffel, Eline Naert, 2019

机译：PRIMMO研究方案：II期研究结合PD-1阻滞剂放射线和免疫调节剂对付宫颈癌和子宫癌
9. PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer [O] . Danny Rischin, Marta Gil-Martin, Antonio González-Martin, 2020

机译：复发或转移性宫颈癌中的PD-1阻断：来自Cemiplimab期I的数据扩张队列和宫颈癌PD-L1表现的表征
10. National Breast and Cervical Cancer Early Detection Program: Summarizing the First 12 Years of Partnerships and Progress Against Breast and Cervical Cancer. 1991-2002 National Report [R] . Ryerson, A. B., Benard, V. B., Major, A. C. 2002

机译：国家乳腺癌和宫颈癌早期检测计划：总结前12年的乳腺癌和宫颈癌合作伙伴关系和进展。 1991-2002国家报告

PD-1 blockade in recurrent or metastatic cervical cancer: Data from cemiplimab phase I expansion cohorts and characterization of PD-L1 expression in cervical cancer

摘要

著录项

引文网络

相似文献

相关主题

期刊订阅