Pivotal efficacy trials of inhaled corticosteroids in asthma

Covar Ronina A.

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Pivotal efficacy trials of inhaled corticosteroids in asthma

机译：吸入糖皮质激素治疗哮喘的关键疗效试验

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Background: Inhaled corticosteroids (ICSs) are the mainstay of daily controller treatment for persistent and uncontrolled asthma. However, many clinicians are wary of ICSs because of safety concerns. Clinicians need to know the underlying efficacy data that support the use of ICSs to weigh efficacy against safety.

机译：背景：吸入性糖皮质激素（ICSs）是持续和不受控制的哮喘日常控制治疗的主要手段。但是，出于安全考虑，许多临床医生对ICS保持戒心。临床医生需要了解支持ICS权衡疗效与安全性的基础功效数据。

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《Annals of allergy, asthma, and immunology》 |2016年第6期|共7页
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Covar Ronina A.;
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正文语种 eng
中图分类医学免疫学;
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1. Pivotal efficacy trials of inhaled corticosteroids in asthma [J] . Covar Ronina A. Annals of allergy, asthma, and immunology . 2016,第6期

机译：吸入糖皮质激素治疗哮喘的关键疗效试验
2. Dupilumab efficacy and safety in adults with uncontrolled persistent asthma despite use of medium-to-high-dose inhaled corticosteroids plus a long-acting beta(2) agonist: a randomised double-blind placebo-controlled pivotal phase 2b dose-ranging trial [J] . Wenzel Sally, Castro Mario, Corren Jonathan, The Lancet . 2016,第10039期

机译：尽管使用中至高剂量吸入皮质类固醇加长效β（2）激动剂，Dupilumab对不受控制的持续性哮喘的成年人的疗效和安全性：一项随机双盲安慰剂对照枢纽性2b剂量范围试验
3. Efficacy and safety evaluation of once-daily fluticasone furoate/vilanterol in Asian patients with asthma uncontrolled on a low- to mid-strength inhaled corticosteroid or low-dose inhaled corticosteroid/long-acting beta2-agonist [J] . Lin Jiangtao, Tang Huaping, Chen Ping, Allergy and asthma proceedings . 2016,第4期

机译：低剂量至中强度吸入皮质类固醇激素或小剂量吸入皮质类固醇/长效β2-激动剂无法控制的亚洲哮喘患者，每日一次糠酸氟替卡松/维兰特罗的疗效和安全性评估
4. Expression of surface markers on peripheral CD4<'+>CD25<'high> T cells in patients with atopic asthma: role of inhaled corticosteroid [C] . Cao Shukun, rnXu Jing, rnShi Lei, Journal of Organ Dysfunction: ISRD 2007 Abstract Book . 2007

机译：特应性哮喘患者外周血CD4'+ CD25 <'high> T细胞表面标志物的表达：吸入糖皮质激素的作用
5. Addition of leukotriene receptor antagonists versus long acting beta agonists to inhaled corticosteroid therapy for asthma treatment in older adults: A retrospective data analysis of effectiveness, safety and cost. [D] . Altawalbeh, Shoroq Mahmoud. 2015

机译：在吸入性糖皮质激素治疗中，将白三烯受体拮抗剂与长效β激动剂相比，用于老年人的哮喘治疗：有效性，安全性和成本的回顾性数据分析。
6. Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long-acting beta-2-agonists in the management of patients diagnosed with asthma and concurrent allergic rhinitis (the RADAR trial) [O] . Paul K Keith, Caroline Koch, Michel Djandji, 2009

机译：孟鲁司特作为吸入性糖皮质激素或吸入性皮质类固醇与长效β-2-激动剂的附加疗法用于诊断为哮喘和并发性变应性鼻炎的患者（RADAR试验）
7. Comparison of efficacy of high dose inhaled corticosteroids with a combination of low dose inhaled corticosteroids and long acting beta2 agonists in patients of moderate persistent asthma : a randomised prospective comparative study [O] . Vivek Sood, Parveen Sharma, Rekha Bansal, 2016

机译：高剂量吸入皮质类固醇与低剂量吸入的皮质类固醇组合的疗效比较和中度持久性哮喘患者的长效β2激动剂：随机前瞻性比较研究

Pivotal efficacy trials of inhaled corticosteroids in asthma

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