Computer-Assisted Nuclear Morphometry in Relation to Metastasis to Regional Lymph Nodes in Canine Hepatoid Adenocarcinomas

摘要

We wish to draw attention to the fact that nuclear morphometry could be used as an additional tool for evaluating the metastatic potential of canine he-patoid adenocarcinomas.Hepatoid gland adenocarcinomas are malignant tumors originating from the circumanal glands, which are modified sebaceous glands. These glands occur only in Canidae and are referred to as hepatoid glands because morphologically the cells resemble hepatocytes. The rate of growth of peri-anal gland adenocarcinoma varies. Metastasis occurs via the lymphatic route to the sublumbar, sacral and internal iliac lymph nodes with subsequent spread to the lung and other organs. Criteria to predict metastases of these tumors are lacking.