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首页> 外文期刊>Analytica chimica acta >Development of a novel liquid chromatography - Evaporative light scattering detection method for bacitracins and applications to quality control of pharmaceuticals
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Development of a novel liquid chromatography - Evaporative light scattering detection method for bacitracins and applications to quality control of pharmaceuticals

机译:新型液相色谱的开发-杆菌肽的蒸发光散射检测方法及其在药物质量控制中的应用

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摘要

A novel liquid chromatography method for the direct determination of bacitracin main components (Bc-A, -B-1, -B-2 and -B-3), a basic, cyclic polypeptide antibiotic, was developed and validated, based on ion pairs formation with trifluoroacetic acid (TFA) and evaporative light scattering detection (ELSD).
机译:基于离子对,开发并验证了一种直接测定杆菌肽主要成分(Bc-A,-B-1,-B-2和-B-3)(一种基本的环状多肽抗生素)的新型液相色谱方法用三氟乙酸(TFA)和蒸发光散射检测(ELSD)形成。

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