Cystathionine gamma-Lyase Deficiency Exacerbates CCl4-Induced Acute Hepatitis and Fibrosis in the Mouse Liver

Ci Lei; Yang Xingyu; Gu Xiaowen; Li Qing; Guo Yang; Zhou Ziping; Zhang Mengjie; Shi Jiahao; Yang Hua; Wang Zhugang; Fei Jian

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Cystathionine gamma-Lyase Deficiency Exacerbates CCl4-Induced Acute Hepatitis and Fibrosis in the Mouse Liver

机译：胱硫胺γ粘酶缺乏加剧了小鼠肝脏中CCL4诱导的急性肝炎和纤维化

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Aims: The present study examined the role of cystathionine gamma-lyase (CSE) in carbon tetrachloride (CCl4)-induced liver damage.

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来源
《Antioxidants and redox signalling》 |2017年第3期|共17页
作者
Ci Lei; Yang Xingyu; Gu Xiaowen; Li Qing; Guo Yang; Zhou Ziping; Zhang Mengjie; Shi Jiahao; Yang Hua; Wang Zhugang; Fei Jian;
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作者单位

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

Shanghai Res Ctr Model Organisms Shanghai Peoples R China;

Tongji Univ Sch Life Sci &

Techonol 1239 Siping Rd Shanghai 200092 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类基础医学;
关键词
hydrogen sulfide; carbon tetrachloride; hepatitis; liver fibrosis;

机译：硫化氢;四氯化碳;肝炎;肝纤维化;

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专利

1. Yu Gan Long Ameliorates Hepatic Fibrosis by Inhibiting PI3K/AKT,Ras/ERK and JAK1/STAT3 Signaling Pathways in CCl4-induced Liver Fibrosis Rats [J] . Hou-gang LI, Peng-tao YOU, Yu XI, 当代医学科学(英文) . 2020,第003期
2. Cystathionine gamma-Lyase Deficiency Exacerbates CCl4-Induced Acute Hepatitis and Fibrosis in the Mouse Liver [J] . Ci Lei, Yang Xingyu, Gu Xiaowen, Antioxidants and redox signalling . 2017,第3期

机译：胱硫胺γ粘酶缺乏加剧了小鼠肝脏中CCL4诱导的急性肝炎和纤维化
3. CXCR3 Deficiency Exacerbates Liver Disease and Abrogates Tolerance in a Mouse Model of Immune-Mediated Hepatitis [J] . Annette Erhardt, Claudia Wegscheid, Benjamin Claass, The journal of immunology . 2011,第9期

机译：CXCR3缺乏症加剧了免疫介导的肝炎的小鼠模型中的肝脏疾病和废除耐受性。
4. CXCR3 Deficiency Exacerbates Liver Disease and Abrogates Tolerance in a Mouse Model of Immune-Mediated Hepatitis. [J] . Erhardt A, Wegscheid C, Claass B, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2011,第9期

机译：CXCR3缺乏症在免疫介导的肝炎小鼠模型中加重了肝脏疾病并降低了耐受性。
5. The Effect of CCl4-induced Acute Liver Injury on the ADAM8 Expression in the Mice [C] . Li San-Qiang, Meng Hong-Ye, Xi Shou-Min, Biomedical Engineering and Biotechnology (iCBEB), 2012 International Conference on . 2012

机译：CCl4诱导的急性肝损伤对小鼠ADAM8表达的影响
6. The role of CXCL9 in host defense during acute viral infection of the CNS and liver in mice: Perspectives using a recombinant mouse hepatitis virus. [D] . Muse, Michael Harold. 2007

机译：CXCL9在小鼠中枢神经系统和肝脏的急性病毒感染过程中在宿主防御中的作用：使用重组小鼠肝炎病毒的观点。
7. Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis [O] . Virginie Carrière, Muhammad Imran Arshad, Jacques Le Seyec, 2017

机译：内源性IL-33缺乏症加重了急性小鼠病毒性肝炎的肝损伤并增加了中性粒细胞的肝内流。
8. Deficiency of cystathionine gamma-lyase and hepatic cholesterol accumulation during mouse fatty liver development [O] . Sarathi Mani, Hongzhu Li, Guangdong Yang, 2015

机译：小鼠脂肪肝脏发育过程中缺乏胱硫氨酸γ-丙基酶和肝胆胆固醇的累积
9. Acute and Chronic Plasma Metabalomic and Liver Transcriptomic Stress Effects in a Mouse Model with Features of Post-Traumatic Stress Disorder. [R] . Gautam, A., D'Arpa, P., Donohue, D. E., 2015

机译：具有创伤后应激障碍特征的小鼠模型中的急性和慢性血浆代谢组和肝转录组应激效应。

Cystathionine gamma-Lyase Deficiency Exacerbates CCl4-Induced Acute Hepatitis and Fibrosis in the Mouse Liver

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