A Novel Non-invasive Effective Method for Potential Treatment of Degenerative Disc Disease: A Hypothesis

摘要

The pathophysiology of the intervertebral discs plays a significant role in the people’s lifequality. There is not adequate research done in the pathogenesis and treatment of intervertebral discdegeneration. Alternately, self-educated physiology offers a novel and noninvasive method to reversethe degenerated discs. In this single case study, report attempts have been made to highlight the effectof the self-educative physiology, on magnetic resonance imaging investigations, of progressivehealing, on the degenerated intervertebral discs. Based on this novel method, an effort has been madeto review literature on the degeneration of intervertebral discs and available mode of treatments andthen to propose a hypothesis for the biochemical mechanisms of healing. The idea is that transforminggrowth factor-β1 from seminal plasma secretions may contribute to releasing the osteogenic protein-1 which induces nucleus pulposus and annulus fibrosus cells in intervertebral discs for repairs.In addition, the patient’s medical history is presented with background information.