Change in hepatic volume profile in potential live liver donors after lifestyle modification for reduction of hepatic steatosis

摘要

Purpose We aimed to evaluate changes in hepatic volume and hemiliver volume percentage in potential liver donors after hepatic steatosis (HS) reduction through lifestyle modification. Methods Fifty liver donor candidates with HS (macrovesicular fat [MaF] >= 20%) underwent abdominal computed tomography (CT) and liver biopsy before (baseline) and after (follow-up) lifestyle modification. According to the change in MaF, subjects were classified as group A (MaF reduction >= 20%, n = 25), and group B (MaF reduction = 20%) after HS reduction through lifestyle modification. Reevaluation of the hepatic volume is required before liver procurement after lifestyle modification in these subjects.