An HPLC-MS/MS Method for the Quantitative Determination of Ticagrelor and its Active Metabolite AR-C124910XX in Human Plasma and its Application to a Clinical Study

Peng Jingbo; Wang Yicheng; Li Mupeng; He Chenjie; Chen Yao; Chen Xiaoping; Ouyang Dongsheng; Huang Yuanfei; Tan Zhirong

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An HPLC-MS/MS Method for the Quantitative Determination of Ticagrelor and its Active Metabolite AR-C124910XX in Human Plasma and its Application to a Clinical Study

机译：一种HPLC-MS / MS方法，用于定量测定人血浆中TiCagreloROR及其活性代谢物Ar-C124910xx及其在临床研究中的应用

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来源
《Current pharmaceutical analysis.》 |2017年第3期|共8页
作者
Peng Jingbo; Wang Yicheng; Li Mupeng; He Chenjie; Chen Yao; Chen Xiaoping; Ouyang Dongsheng; Huang Yuanfei; Tan Zhirong;
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原文格式 PDF
正文语种 eng
中图分类药学;
关键词
AR-C124910XX; method of validation; Ticagrelor; HPLC-MS/MS; Chinese male volunteers; pharmacokinetics;

机译：AR-C124910xx;验证方法;TicagreloLor;HPLC-MS / MS;中国男性志愿者;药代动力学;

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5. Determination of unbound ticagrelor and its active metabolite (AR-C124910XX) in human plasma by equilibrium dialysis and LC-MS/MS [J] . Sillén H., Cook M., Davis P. Journal of chromatography, B. Analytical technologies in the biomedical and life sciences . 2011,第23期

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An HPLC-MS/MS Method for the Quantitative Determination of Ticagrelor and its Active Metabolite AR-C124910XX in Human Plasma and its Application to a Clinical Study

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