Acetate Suppresses Lipopolysaccharide-stimulated Nitric Oxide Production in Primary Rat Microglia but not in BV-2 Microglia Cells

Moriyama Mitsuaki; Nishimura Yasunori; Kurebayashi Ryosuke; Minamihata Tomoki; Kawabe Kenji; Takano Katsura; Nakamura Yoichi

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Acetate Suppresses Lipopolysaccharide-stimulated Nitric Oxide Production in Primary Rat Microglia but not in BV-2 Microglia Cells

机译：醋酸盐抑制原代大鼠小胶质细胞的脂多糖刺激的一氧化氮产生，但不含BV-2微胶质细胞

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Aims: To show that acetate attenuates neuroinflammatory responses in activated microglia.

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来源
《Current molecular pharmacology》 |2021年第2期|共8页
作者
Moriyama Mitsuaki; Nishimura Yasunori; Kurebayashi Ryosuke; Minamihata Tomoki; Kawabe Kenji; Takano Katsura; Nakamura Yoichi;
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作者单位

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

Osaka Prefecture Univ Lab Integrat Physiol Vet Sci 1-58 Rinku Ourai Kita Osaka 5988531 Japan;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Acetate; microglia; neuroinflammation; nitric oxide; BV-2 cell line;

机译：醋酸盐;微胶质细胞;神经引发;一氧化氮;BV-2细胞系;

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1. Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase [J] . Ran Xiao1, Shan Li2, Qian Cao3, 中国病毒学：英文版 . 2017,第003期
2. Effect of curcumin on nitric oxide synthase expression in Iipopolysaccharide-activated microglia cells and the anti-oxidative effect of curcumin [J] . 中国神经再生研究（英文版） . 2007,第012期
3. Suppressive effects of acetone extract from the stem bark of three Acacia species on nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 macrophage cells [J] . Kandhasamy Sowndhararajan, Rameshkumar Santhanam, Sunghyun Hong, 亚太热带生物医学杂志（英文版） . 2016,第008期
4. Suppressive effects of acetone extract from the stem bark of three Acacia species on nitric oxide production in lipopolysaccharide-stimulated RAW 264.7 macrophage cells [J] . Kandhasamy Sowndhararajan, Rameshkumar Santhanam, Sunghyun Hong, 亚太热带生物医学杂志：英文版 . 2016,第008期
5. Flavonoids isolated from Lespedeza cuneata G. Don and their inhibitory effects on nitric oxide production in lipopolysaccharide-stimulated BV-2 microglia cells [J] . Guijae Yoo, Seon Ju Park, Taek Hwan Lee, Pharmacognosy magazine . 2015,第43期

机译：从Lespedeza cuneata G. Don分离出的类黄酮及其对脂多糖刺激的BV-2小胶质细胞中一氧化氮产生的抑制作用
6. Nitric Oxide Inhibits Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase Expression and Its Own Production Through the cGMP Signaling Pathway in Murine Microglia BV-2 Cells [J] . Akiko Yamamuro, Atsushi Kasai, Nobuo Takeda, Journal of pharmacological sciences. . 2010,第2期

机译：一氧化氮抑制脂多糖诱导的诱导型一氧化氮合酶表达及其通过cGMP信号通路在小鼠小胶质细胞BV-2细胞中的自身产生。
7. Nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cGMP signaling pathway in murine microglia BV-2 cells [J] . YoshiokaY., TakedaN., YamamuroA., Journal of pharmacological sciences. . 2010,第2期

机译：一氧化氮通过cGMP信号通路抑制鼠小胶质细胞BV-2细胞中脂多糖诱导的一氧化氮合酶的表达及其自身产生
8. Oxidative Toxicity in BV-2 Microglia Cells: Sesamolin Neuroprotection of H_2O_2 Injury Involving Activation of p38 Mitogen-Activated Protein Kinase [C] . ROLIS CHIEN-WEI HOU, CHIA-CHUAN WU, JING-RONG HUANG, Asian Society for Mitochondrial Research and Medicine . 2005

机译：BV-2微胶质细胞中的氧化毒性：H_2O_2损伤的SESAMOLIN神经保护损伤涉及P38丝裂原激活蛋白激酶的激活
9. The Antioxidant and Anti-inflammatory Basis of the Neuroprotective Effect of Thymoquinone in Activated BV-2 Murine Microglia Cells [D] . Cobourne-Duval, Makini K. 2018

机译：活化BV-2鼠髓微胶质细胞中胸腺酮神经保护作用的抗氧化和抗炎基础
10. Valproic acid attenuates nitric oxide and interleukin-1β production in lipopolysaccharide-stimulated iron-rich microglia [O] . Nootchanat Mairuae, Poonlarp Cheepsunthorn -1

机译：丙戊酸减弱脂多糖刺激的富铁小胶质细胞中的一氧化氮和白细胞介素1β的产生
11. Nitric Oxide Inhibits Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase Expression and Its Own Production Through the cGMP Signaling Pathway in Murine Microglia BV-2 Cells [O] . Yasuhiro Yoshioka, Nobuo Takeda, Akiko Yamamuro, 2010

机译：一氧化氮抑制脂多糖诱导的诱导型一氧化氮合酶表达及其通过鼠微胶质细胞BV-2细胞中的CGMP信号通路的产生
12. Increase in Blood-Brain Barrier Perrmeability, Oxidative Stress, and Activated Microglia in a Rat Model of Blast-Induced Traumatic Brain Injury [R] . Readnower, R. D., Chavko, M., Adeeb, S., 2010

机译：爆炸致颅脑损伤大鼠血脑屏障通透性，氧化应激和活化小胶质细胞增加

Acetate Suppresses Lipopolysaccharide-stimulated Nitric Oxide Production in Primary Rat Microglia but not in BV-2 Microglia Cells

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