Incorporating K-mers Highly Correlated to Epigenetic Modifications for Bayesian Inference of Gene Interactions

摘要

Objective: A gene interaction network, along with its related biological features, has an important role in computational biology. Bayesian network, as an efficient model, based on probabilistic concepts is able to exploit known and novel biological casual relationships between genes. The success of Bayesian networks in predicting the relationships greatly depends on selecting priors.