Biamperometric Determination of Tetracycline in Pharmaceuticals

摘要

A fast,reliable,and low cost biamperometric flow-injection method,with an error of 1.3% and an analytical throughput of 55 samples h~(-1),for determination of tetracycline hydrochloride in pharmaceuticals capsules is proposed.The analytical curve was linear (r = 0.998) in the range 10 to 50 mg l~(-1) using Fe(CN)6~(3-) and NaOH solutions as reagent and carrier stream/supporting electrolyte,respectively.A relative standard deviation of 1.6% (10 sequential injections of 30.0 mg l~(-1)) was verified with detection and quantification limits of 0.6 and 3.4 mg 1~(_1),respectively.