DETERMINATION OF PHTHALATE ESTERS IN WINE USING DISPERSIVE LIQUID-LIQUID MICROEXTRACTION AND GAS CHROMATOGRAPHY

摘要

A simple and rapid efficient method was developed for the determination of phthalate esters using dispersive liquid-liquid microextraction followed by gas chromatography with flame ionization detection. A mixture of isopropanol (0.75mL, dispersant) and carbon tetrachloride (30 lL, extractant) with sodium chloride (1%, w/v) was used for extraction. Under optimum conditions, the method provided linear calibration curves between 0.5 and 200 lgL~(-1) for dibutyl phthalate, and 1.0 and 200 lgL~(-1) for butyl benzyl phthalate, diethyl phthalate, and diisooctyl phthalate. The relative standard deviations for intra-day and inter-day analyses were less than 5.8% and 6.9%, respectively, with enrichment factors between 229 and 424. Two wine samples were analyzed with recoveries between 70.1% and 119.3%.