Multicentric Reticulohistiocytosis Mimicking Malignancy on F-18-FDG PET/CT

摘要

We report the case of a 75-year-old woman who underwent 18F-FDG PET/CT to evaluate the recurrence of urothelial carcinoma. PET/CT showed 18F-FDG-avid muscles and lymph nodes, mimicking recurrence. However, 18F-FDG uptake was also seen in multiple joints and subcutaneous tissue, representing an uncommon finding for recurrence. Further history taking revealed she had been pathologically diagnosed with multicentric reticulohistiocytosis ( MRH) from skin biopsy, and the 18F-FDG PET/CT findings were consistent with MRH, a rare systemic inflammatory granulomatous disease of unknown etiology. Knowledge of the characteristic 18F-FDG PET/CT features of MRH is important to differentiate MRH from malignancy.