NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma

Weiss Tobias; Schneider Hannah; Silginer Manuela; Steinle Alexander; Pruschy Martin; Polic Bojan; Weller Michael; Roth Patrick

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NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma

机译：NKG2D依赖性化疗和放疗对胶质母细胞瘤的抗肿瘤作用

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Purpose: NKG2D is a potent activating immune cell receptor, and glioma cells express the cognate ligands (NKG2DL). These ligands are inducible by cellular stress and temozolomide (TMZ) or irradiation (IR), the standard treatment of glioblastoma, could affect their expression. However, a role of NKG2DL for the efficacy of TMZ and IR has never been addressed.

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《Clinical cancer research: an official journal of the American Association for Cancer Research》 |2018年第4期|共14页
作者
Weiss Tobias; Schneider Hannah; Silginer Manuela; Steinle Alexander; Pruschy Martin; Polic Bojan; Weller Michael; Roth Patrick;
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作者单位

Univ Hosp Zurich Dept Neurol Frauenklin Str 26 CH-8091 Zurich Switzerland;

Univ Hosp Zurich Dept Neurol Frauenklin Str 26 CH-8091 Zurich Switzerland;

Univ Hosp Zurich Dept Neurol Frauenklin Str 26 CH-8091 Zurich Switzerland;

Goethe Univ Frankfurt Inst Mol Med Frankfurt Germany;

Univ Zurich Zurich Switzerland;

Univ Rijeka Fac Med Dept Histol &

Embryol Rijeka Croatia;

Univ Hosp Zurich Dept Neurol Frauenklin Str 26 CH-8091 Zurich Switzerland;

Univ Hosp Zurich Dept Neurol Frauenklin Str 26 CH-8091 Zurich Switzerland;

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正文语种 eng
中图分类肿瘤学;
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5. NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma [J] . Weiss Tobias, Schneider Hannah, Silginer Manuela, Clinical cancer research: an official journal of the American Association for Cancer Research . 2018,第4期

机译：化疗和放疗对胶质母细胞瘤的NKG2D依赖性抗肿瘤作用
6. Enhanced antitumor effects of radiotherapy combined local nimustine delivery rendezvousing with oral temozolomide chemotherapy in glioblastoma patients [J] . Dong-Yi Yang, Xing-Yao Bu, Zhi-Long Zhou, Journal of Cancer Research and Therapeutics . 2018,第1期

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7. THE NKG2D SYSTEM MEDIATES ANTI-TUMOR EFFECTS OF CHEMOTHERAPY AND RADIOTHERAPY AGAINST GLIOBLASTOMA [J] . Weiss T., Schneider H., Silginer M., Neuro-Oncology . 2016,第suppla4期

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8. Low Grade Glioma Growth Modeling Considering Chemotherapy and Radiotherapy Effects from Magnetic Resonance Images [C] . Ahmed Elazab, Hongmin Bai, Xiaodong Zhang, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2017

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11. Histone deacetylase enzymes and selective histone deacetylase inhibitors for antitumor effects and enhancement of antitumor immunity in glioblastoma [O] . Caleb J. Yelton, Swapan K. Ray 2018

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机译：使用抗血管生成和抗肿瘤治疗增强前列腺癌放射治疗

NKG2D-Dependent Antitumor Effects of Chemotherapy and Radiotherapy against Glioblastoma

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