Analytical Applications of Cooperative Interactions Associated with Charge Transfer in Cyanometalate Electrodes: Analysis of Sodium and Potassium in Human Whole Blood

摘要

Nickel electrodes chemically modified with an interracial layer of nickel ferrocyanide are shown to be of analytical utility for simultaneously sensing sodium and potassium ions in aqueous solutions, human whole blood serum, and human whole blood, By controlling the charge-transfer characteristics of this versatile interface, interfering blood proteins and potential interferences associated with other alkali cations can be avoid. A solid-state model which explains the excellent, simultaneous selectivity and sensitivity of the nickel ferricyanide interface is proposed.