Two New Benzazepine Alkaloids from Thalictrum wangii and their Anti-Rotavirus Activity

Wu Fang; Liu Lu; Zhu Ya-Ning; Lv Na; Luo Dian; Zhu Li-Jun; Dong Miao; Zhou Min; Wang Wei-Guang; Hu Qiu-Fen; Li Zhi-Gang

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Two New Benzazepine Alkaloids from Thalictrum wangii and their Anti-Rotavirus Activity

机译：来自ThaliCtrum Wangii的两种新的苯并嗪生物碱及其抗轮状病毒活性

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摘要

Two new benzazepine alkaloids (1 and 2) were isolated from the whole plants of Thalictrum wangii. Their structures were determined by means of HR-ESI-MS and extensive 1D and 2D NMR spectroscopic studies. Compounds 1 and 2 were tested for their anti-rotavirus activity. The results revealed that compounds 1 and 2 exhibited potent anti-rotavirus activity with TI values of 17.9 and 17.6, respectively.

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来源
《Chemistry of Natural Compounds 》 |2021年第2期| 共4页
作者
Wu Fang; Liu Lu; Zhu Ya-Ning; Lv Na; Luo Dian; Zhu Li-Jun; Dong Miao; Zhou Min; Wang Wei-Guang; Hu Qiu-Fen; Li Zhi-Gang;
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作者单位

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Yunnan Minzu Univ State Ethn Affairs Commiss Key Lab Chem Ethn Med Resources Kunming 650031 Yunnan Peoples R China;

Agr Informat Ctr Agr Dept Kunming 650032 Yunnan Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类化学 ;
关键词
benzazepine alkaloids; Thalictrum wangii; anti-rotavirus activity;

机译：Benzazepine生物碱;Thalictrum Wangii;抗轮状病毒活动;

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1. Two New Oxoaporphine Alkaloids from Thalictrum elegans [J] . 梁志远, 杨小生, 汪冶, 中国化学：英文版 . 2005 ,第007期
2. Study on the Ring Eulargment Reaction: Synthesis of 7,8,13, 13a-tetrahydroisoindolo1,2-b3benzazepine and 5,6,8,9,14,14a-hexahydroisoquino1,2-b3benzazepine [J] . 中国化学快报（英文版） . 2001 ,第001期
3. TWO NEW BENZAZEPINE ALKALOIDS FROM Thalictrum wangii AND THEIR ANTI-ROTAVIRUS ACTIVITY [J] . Fang Wu, Lu Liu, Ya-Ning Zhu Химия природных соединений . 2021 ,第2期

机译：来自ThaliCtrum Wangii的两种新的苯并嗪生物碱及其抗轮状病毒活性
4. THREE NEW BENZAZEPINE ALKALOIDS FROM THALICTRUM CIRRHOSUM AND THEIR ANTI-ROTAVIRUS ACTIVITY [J] . Hu Qiu-Fen, Luo Dian, Lv Na, Heterocycles: An International Journal for Reviews and Communications in Heterocyclic Chemistry . 2020 ,第8期

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5. Antitumor aporphine alkaloids from Thalictrum wangii [J] . Jin Qiong, Yang Dong, Dai Zhi, Fitoterapia . 2018 ,第期

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7. Part I. Alkaloidal constituents of selected fractions of Thalictrum angustifolium L. and Thalictrum wangii Boivin (Ranunculaceae). Part II. A revision of the structure of thalprzewalskiinone. The synthesis of 2-methyl-6,7-dimethoxy-3'-methoxy-4'-hydroxyoxobenzylisoquinoline and 2-methyl-6,7-dimethoxy-3'-hydroxy-4'-methoxyoxobenzylisoquinoline. [D] . Al-Howiriny, Tawfeq Abdullah. 2000

机译：第一部分。拟南芥和拟南芥（Ranunculaceae）的选定部分的生物碱成分。第二部分thalprzewalskiinone结构的修订。 2-甲基-6,7-二甲氧基-3'-甲氧基-4'-羟基氧苄基异喹啉和2-甲基-6,7-二甲氧基-3'-羟基-4'-甲氧基氧苄基异喹啉的合成。
8. Comparison of Anticancer Activity and HPLC-DAD Determination of Selected Isoquinoline Alkaloids from Thalictrum foetidum Berberis sp. and Chelidonium majus Extracts [O] . Anna Petruczynik, Tomasz Tuzimski, Tomasz Plech, 2019

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9. Alkaloids of Thalictrum. VIII. Isolation of Thalidasine from Thalictrum rugosum [O] . TOSHIAKI TOMIMATSU, MITSUKO HASHIMOTO, JACKL. BEAL 1968

机译：丘脑的生物碱。 VIII。从丘脑藤岩中孤立
10. Isolation, Biosynthesis and Biological Activity of Alkaloids of Tylophora Asthmatica, a Versatile Medicinal Plant [R] . Mulchandani, N. B. 1987

机译：多功能药用植物Tylophora asthmatica生物碱的分离，生物合成和生物活性

Two New Benzazepine Alkaloids from Thalictrum wangii and their Anti-Rotavirus Activity

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