Synthesis of New 18 beta-H-Glycyrrhetic Acid Amides with Several 2-Amino-5-Alkylaminothiadiazoles

摘要

A series of new 3-O-acetyl-18 beta -H-glycyrrhetic acid amides with S-containing heterocyclic amines (2-aminothiadiazole; 2-amino-5-methyl-, ethyl-, propyl-, and isobutylthiadiazole; 2-aminothiazole) were synthesized. The structures of the new amides were established using UV, IR, PMR, and C-13 NMR spectroscopy and mass spectrometry.