SURFACE ENHANCED RAMAN SCATTERING FROM AN ETCHED POLYMER SUBSTRATE

摘要

An etched polymer was evaluated as a substrate suitable for routine SER analysis and was found to perform similarly to crossed gratings and posted quartz wafers, Silver particles were layered onto sheets of etched poly-(ethylene terephthalate) by chemical reduction, sputtering, and vapor deposition. Enhancement factors ranged from 10(4) to > 10(5) for crystal violet on chemically reduced and sputtered surfaces, respectively. Ranges of linearity up to 3 orders of magnitude were attained with limits of detection of similar to 5 pg, The variability of response was <20% RSD for both routinely and painstakingly prepared samples. To induce enhancements beyond those possible from the dry substrate, a thin film of water was held on the analyte-treated substrate surface in a liquid state. Typical spectra of nine analytes with amino, carboxylate, and/or nitro groups were collected from the most active substrate.