MRI activity and extended interval of Natalizumab dosing regimen: a multicentre Italian study

De Mercanti Stefania Federica; Signori Alessio; Cordioli Cinzia; Signoriello Elisabetta; Lus Giacomo; Bonavita Simona; Abbadessa Gianmarco; Lavorgna Luigi; Maniscalco Giorgia Teresa; Curti Erica; Lorefice Lorena; Cocco Eleonora; Nociti Viviana; Mirabella Massimiliano; Baroncini Damiano; Mataluni Giorgia; Landi Doriana; Petruzzo Martina; Lanzillo Roberta; Gandoglia Ilaria; Laroni Alice; Frangiamore Rita; Sartori Arianna; Cavalla Paola; Costantini Gianfranco; Capra Ruggero; Sormani Maria Pia; Clerico Marinella

首页> 外文期刊>Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology >MRI activity and extended interval of Natalizumab dosing regimen: a multicentre Italian study

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MRI activity and extended interval of Natalizumab dosing regimen: a multicentre Italian study

机译：Natalizumab给药队长的MRI活动和延长间隔：多期中心意大利研究

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Background: To minimize the risk of Progressive Multifocal Leukoencephalopathy and rebound in JCV-positive multiple sclerosis (MS) patients after 24 natalizumab doses, it has been proposed to extend the administrations interval. The objective is to evaluate the EID efficacy on MRI activity compared with the standard interval dosing (SID).

机译：背景：为了最大限度地降低24剂纳他利珠单抗后JCV阳性多发性硬化（MS）患者发生进行性多灶性白质脑病和反弹的风险，有人建议延长给药间隔。目的是与标准间隔给药（SID）相比，评估EID对MRI活动的疗效。

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来源
《Journal of the Neurological Sciences: Official Bulletin of the World Federation of Neurology》 |2021年第1期|共4页
作者
De Mercanti Stefania Federica; Signori Alessio; Cordioli Cinzia; Signoriello Elisabetta; Lus Giacomo; Bonavita Simona; Abbadessa Gianmarco; Lavorgna Luigi; Maniscalco Giorgia Teresa; Curti Erica; Lorefice Lorena; Cocco Eleonora; Nociti Viviana; Mirabella Massimiliano; Baroncini Damiano; Mataluni Giorgia; Landi Doriana; Petruzzo Martina; Lanzillo Roberta; Gandoglia Ilaria; Laroni Alice; Frangiamore Rita; Sartori Arianna; Cavalla Paola; Costantini Gianfranco; Capra Ruggero; Sormani Maria Pia; Clerico Marinella;
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作者单位

Univ Torino San Luigi Gonzaga Hosp Neurol Unit Clin &

Biol Sci Dept Turin Italy;

Univ Genoa Sect Biostat Dept Hlth Sci Genoa Italy;

Spedali Civili Brescia Multiple Sclerosis Ctr Presidio Montichiari Brescia Italy;

Univ Naples 2 Dept Med Surg Neurol Metab &

Aging Sci Naples Italy;

Univ Naples 2 Dept Med Surg Neurol Metab &

Aging Sci Naples Italy;

AOU Univ Campania Luigi Vanvitelli Clin Neurol Naples Italy;

AOU Univ Campania Luigi Vanvitelli Clin Neurol Naples Italy;

AOU Univ Campania Luigi Vanvitelli Clin Neurol Naples Italy;

Neurol Clin Naples Italy;

Univ Parma Dept Med &

Surg Neurol Unit Parma Italy;

Univ Cagliari Binaghi Hosp Dept Med Sci &

Publ Hlth Multiple Sclerosis Ctr Cagliari Italy;

Univ Cagliari Binaghi Hosp Dept Med Sci &

Publ Hlth Multiple Sclerosis Ctr Cagliari Italy;

Fdn Policlin Univ Gemelli Multiple Sclerosis Ctr Neurosci Area Neurosci Aging Head &

Neck &

Fdn Policlin Univ Gemelli Multiple Sclerosis Ctr Neurosci Area Neurosci Aging Head &

Neck &

ASST Valle Olona Presidio Osped Gallarate Ctr Sclerosi Multipla Busto Arsizio Italy;

Policlin Tor Vergata UOSD Ctr Riferimento Reg Sclerosi Multipla Dipartimento Neurosci Rome Italy;

Policlin Tor Vergata UOSD Ctr Riferimento Reg Sclerosi Multipla Dipartimento Neurosci Rome Italy;

Univ Naples Federico II Multiple Sclerosis Ctr Dept Neurosci Reprod Sci &

Odontostomatol Naples;

Univ Naples Federico II Multiple Sclerosis Ctr Dept Neurosci Reprod Sci &

Odontostomatol Naples;

Univ Genoa Dept Neurosci Rehabil Ophthalmol Genet Matenal &

Ctr Excellence Biomed Res Genoa;

IRCCS Osped Policlin San Martino Genoa Italy;

IRCCS Fdn Neurol Inst C Besta Dept Neuroimmunol &

Neuromuscular Dis Milan Italy;

Azienda Osped Univ Osped Riuniti Trieste Neurol Unit Azienda Sanitaria Univ Integrata Clin Neurol;

Torino Univ Hosp Dept Neurosci Citta Salute &

Sci Turin Italy;

Torino Univ Hosp Dept Neurosci Citta Salute &

Sci Turin Italy;

Spedali Civili Brescia Multiple Sclerosis Ctr Presidio Montichiari Brescia Italy;

Univ Torino San Luigi Gonzaga Hosp Neurol Unit Clin &

Biol Sci Dept Turin Italy;

Univ Torino San Luigi Gonzaga Hosp Neurol Unit Clin &

Biol Sci Dept Turin Italy;

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原文格式 PDF
正文语种 eng
中图分类神经病学;
关键词
Multiple sclerosis; Natalizumab; Extended dose; Magnetic resonance imaging; Efficacy;

机译：多发性硬化;Natalizumab;延长剂量;磁共振成像;功效;

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MRI activity and extended interval of Natalizumab dosing regimen: a multicentre Italian study

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