The effect of Bu Shen Huo Xue Tang on autoimmune premature ovarian insufficiency via Modulation of the Nrf2/Keap1 signaling pathway in mice

Chen Si; Lu Yan; Chen Yue; Xu Jindi; Chen Lulu; Zhao Weibo; Wang Tingting; Wang Hui; Wang Peijuan

首页> 外文期刊>Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs >The effect of Bu Shen Huo Xue Tang on autoimmune premature ovarian insufficiency via Modulation of the Nrf2/Keap1 signaling pathway in mice

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The effect of Bu Shen Huo Xue Tang on autoimmune premature ovarian insufficiency via Modulation of the Nrf2/Keap1 signaling pathway in mice

机译：Bu Shen Huo Xue唐对小鼠NRF2 / Keap1信号通路的自身免疫过早卵巢功能不全的影响

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Ethnopharmacological relevance: Bu Shen Huo Xue Tang (BSHXT) is a traditional Chinese medicine formula that is clinically used in the treatment of premature ovarian insufficiency (POI). However, its therapeutic mechanism remains unclear.

机译：民族药理学相关性：补肾活血汤（BSHXT）是一种中药配方，临床上用于治疗卵巢早衰（POI）。然而，其治疗机制尚不清楚。

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来源
《Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs》 |2021年第1期|共11页
作者
Chen Si; Lu Yan; Chen Yue; Xu Jindi; Chen Lulu; Zhao Weibo; Wang Tingting; Wang Hui; Wang Peijuan;
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作者单位

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Affiliated Hosp Integrated Tradit Chinese &

Weste Nanjing 210028;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Affiliated Hosp Integrated Tradit Chinese &

Weste Nanjing 210028;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

Nanjing Univ Chinese Med Clin Med Coll 3 Nanjing 210028 Peoples R China;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
Bu Shen Huo Xue Tang; Premature ovarian insufficiency; Nrf2; Keap1 signaling pathway; Oxidative stress; Autoimmunity;

机译：bus很hu ox UE tang;premature ovarian insufficiency;NR法2;K EAP1 signaling pathway;oxidative stress;autoimmunity;

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专利

1. Comparison of effect of granules and herbs of Bu-Shen-Yi-Qi-Tang on airway inflammation in asthmatic mice [J] . Wei Ying, Lyu Yubao, Li Mihui, 中华医学杂志（英文版） . 2014,第022期
2. Protective function of Bu Shen Huo Xue formula on the immunity of B6AF1 mice with experimental autoimmune premature ovarian failure [J] . Wang Peijuan, Lu Yan, Chen Si, Experimental and therapeutic medicine . 2018,第4aPta1期

机译：Bu Shen Huo Xue公式对B6AF1小鼠免疫的保护功能，实验性自身免疫早期卵巢衰竭
3. Bu Shen Huo Xue decoction restores endometrial leukemia-inhibitory factor but not Angiopoietin-2 expression, and improves uterine receptivity in the controlled ovarian stimulation rat model [J] . Gong Xin, Lou Jiaoying, Lu Qiudan, Experimental and therapeutic medicine . 2015,第3期

机译：补肾活血汤能恢复子宫内膜白血病抑制因子而不是血管生成素-2的表达，并能改善可控制性卵巢刺激大鼠模型的子宫接受能力
4. Bu‐Shen‐Huo‐Xue‐Fang modulates nucleus pulposus cell proliferation and extracellular matrix remodeling in intervertebral disk degeneration through miR‐483 regulation of Wnt pathway [J] . Yang Shaofeng, Li Linghui, Zhu Liguo, Journal of cellular biochemistry. . 2019,第12期

机译：Bu-Shen-Huo-Zhu-fang通过MiR-483调节Wnt途径调节椎间盘退化中的核心细胞增殖和细胞外基质重塑
5. Protective function of Bu Shen Huo Xue formula on the immunity of B6AF1 mice with experimental autoimmune premature ovarian failure [O] . Peijuan Wang, Yan Lu, Si Chen, -1

机译：补肾活血方对实验性自身免疫性卵巢早衰小鼠B6AF1免疫的保护作用。
6. Bu-Shen-Huo-Xue Decoction Ameliorates Diabetic Nephropathy by Inhibiting Rac1/PAK1/p38MAPK Signaling Pathway in High-Fat Diet/Streptozotocin-Induced Diabetic Mice [O] . Weisong Wang, Hongping Long, Wei Huang, 2020

机译：Bu-Shen-Huo-Xue汤剂通过抑制高脂饮食/链脲佐菌素诱导的糖尿病小鼠抑制RAC1 / PAK1 / P38MAPK信号通路来改善糖尿病肾病

The effect of Bu Shen Huo Xue Tang on autoimmune premature ovarian insufficiency via Modulation of the Nrf2/Keap1 signaling pathway in mice

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