Stability of interleukin-1 beta,-4,-6,-8,-10,-13, interferon-gamma and tumor necrosis factor-alpha in human sera after repetitive freeze-thaw cycles and long storage

摘要

Introduction: Cytokines (CKs) are one of the key components of the molecular network modulating multiple immunological interactions. Within such biological systems, CKs functions are associated with several processes, thus quantification of these analytes in serum samples, as well as a faithful determination of its concentration, are crucial for the translational aspect of many studies.