Utilization of Maltodextrin-Based Enantioselective,Potentiometric Membrane Electrodes for the Enantioselective Assay of S-Flurbiprofen

摘要

Three enantioselective,potentiometric membrane electrodes(EPMEs)based on carbon paste impregnated with different maltodextrins [dextrose equivalent(DE)(DE 4.0-7.0(I),13-17(II),16.5-19.5(III)],were proposed as chiral selectors for the assay of S-flurbiprofen raw materials and from its pharmaceutical for-mulation,Froben 100~(~R)tablets.The best response and enantioselectivity were obtained when maltodextrin with lower DE was used for the electrode design.The three EPMEs showed very low detection limits.The surfaces of the electrodes are easily renewable by simply polishing on an alumina paper.