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Poly(l-lactic acid)/alkali lignin composites: properties, biocompatibility, cytotoxicity and antimicrobial behavior

机译:聚(L-乳酸)/碱木质素复合材料:性质,生物相容性,细胞毒性和抗微生物行为

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摘要

In this study, poly(L-lactic acid) (PLA)/low molar mass alkali lignin (aL) (1%, 5% and 10% w/w) composites were prepared primarily for a comprehensive understanding of the effect of aL on their antimicrobial properties, biocompatibility and cytotoxic behavior. The properties were evaluated by Fourier transform infrared spectroscopy, scanning electron microscopy, differential scanning calorimetry, thermogravimetry and X-ray diffraction. The mechanical, water vapor barrier properties and photodegradability were analyzed as well. The results showed a significant inhibiting effect of aL on the crystallization behavior of PLA, increased water barrier properties (up to 73%) and photodegradability. PLA/aL composites showed a tenfold reduction in Gram-positive bacteria viability, very good cellular response and very low cytotoxicity levels, thus validating these materials as non-cytotoxic and with high potential to be used as food packaging.
机译:本研究主要制备了聚L-乳酸(PLA)/低摩尔质量碱木质素(aL)(1%、5%和10%w/w)复合材料,以全面了解aL对其抗菌性能、生物相容性和细胞毒性的影响。通过傅里叶变换红外光谱、扫描电子显微镜、差示扫描量热法、热重法和X射线衍射对其性能进行了评估。并对其力学性能、水蒸气阻隔性能和光降解性能进行了分析。结果表明,铝对聚乳酸的结晶行为有明显的抑制作用,提高了聚乳酸的阻水性能(高达73%)和光降解性能。PLA/aL复合材料的革兰氏阳性菌活性降低了10倍,细胞反应非常好,细胞毒性水平非常低,因此验证了这些材料是非细胞毒性的,具有很高的食品包装潜力。

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  • 来源
    《Journal of Materials Science》 |2021年第24期|共16页
  • 作者单位

    Ss Cyril &

    Methodius Univ Fac Technol &

    Met Rudjer Boskovic 16 Skopje 1000 North Macedonia;

    Ss Cyril &

    Methodius Univ Fac Technol &

    Met Rudjer Boskovic 16 Skopje 1000 North Macedonia;

    Univ Basque Country UPV EHU Joxe Mari Korta Ctr POLYMAT Avda Tolosa 72 Donostia San Sebastian 20018 Spain;

    Univ Bucharest Dept Biochem &

    Mol Biol Bucharest 050095 Romania;

    Univ Bucharest Res Inst Bucharest 050095 Romania;

    Univ Bucharest Dept Biochem &

    Mol Biol Bucharest 050095 Romania;

    Univ Bucharest Dept Biochem &

    Mol Biol Bucharest 050095 Romania;

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  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类 工程材料学;
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