Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units A Randomized Clinical Trial

Blackwood Bronagh; Tume Lyvonne N.; Morris Kevin P.; Clarke Mike; McDowell Cliona; Hemming Karla; Peters Mark J.; McIlmurray Lisa; Jordan Joanne; Agus Ashley; Murray Margaret; Parslow Roger; Walsh Timothy S.; Macrae Duncan; Easter Christina; Feltbower Richard G.; McAuley Daniel F.

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Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units A Randomized Clinical Trial

机译：镇静和呼吸机解放方案对儿科重症监护单位侵袭机械通气持续时间的效果对随机临床试验

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IMPORTANCE There is limited evidence on the optimal strategy for liberating infants and children from invasive mechanical ventilation in the pediatric intensive care unit.

机译：重要性在儿科重症监护病房，将婴幼儿从有创机械通气中解放出来的最佳策略的证据有限。

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《JAMA: the Journal of the American Medical Association》 |2021年第5期|共10页
作者
Blackwood Bronagh; Tume Lyvonne N.; Morris Kevin P.; Clarke Mike; McDowell Cliona; Hemming Karla; Peters Mark J.; McIlmurray Lisa; Jordan Joanne; Agus Ashley; Murray Margaret; Parslow Roger; Walsh Timothy S.; Macrae Duncan; Easter Christina; Feltbower Richard G.; McAuley Daniel F.;
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作者单位

Queens Univ Belfast Wellcome Wolfson Inst Expt Med 97 Lisburn Rd Belfast BT9 7BL Antrim North;

Univ Salford Sch Hlth &

Soc Manchester Lancs England;

Birmingham Womens &

Childrens NHS Fdn Trust Birmingham W Midlands England;

Queens Univ Belfast Ctr Publ Hlth Sch Med Dent &

Biomed Sci Belfast Antrim North Ireland;

Royal Hosp Northern Ireland Clin Trials Unit Belfast Antrim North Ireland;

Univ Birmingham Birmingham W Midlands England;

Great Ormond St Hosp Sick Children London England;

Queens Univ Belfast Wellcome Wolfson Inst Expt Med 97 Lisburn Rd Belfast BT9 7BL Antrim North;

Queens Univ Belfast Wellcome Wolfson Inst Expt Med 97 Lisburn Rd Belfast BT9 7BL Antrim North;

Royal Hosp Northern Ireland Clin Trials Unit Belfast Antrim North Ireland;

Royal Hosp Northern Ireland Clin Trials Unit Belfast Antrim North Ireland;

Univ Leeds Leeds Inst Data Analyt Sch Med Leeds W Yorkshire England;

Univ Edinburgh Usher Inst Populat Hlth Sci Edinburgh Midlothian Scotland;

Royal Brompton Hosp London England;

Univ Birmingham Birmingham W Midlands England;

Univ Leeds Leeds Inst Data Analyt Sch Med Leeds W Yorkshire England;

Queens Univ Belfast Wellcome Wolfson Inst Expt Med 97 Lisburn Rd Belfast BT9 7BL Antrim North;

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原文格式 PDF
正文语种 eng
中图分类医药、卫生;
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专利

1. Clinical application of bedside fiber-optic bronchoscopy in mechanically ventilated children in a pediatric intensive care unit [J] . CHAO Jian-xin, HONG Shao-xian, ZHU Zhen-hong, 中华医学杂志（英文版） . 2013,第005期
2. Distribution and antibiotic resistance of pathogens isolated from ventilator-associated pneumonia patients in pediatric intensive care unit [J] . Xiao-fang Cai, Ji-min Sun, Lian-sheng Bao, 世界急诊医学杂志(英文版) . 2011,第002期
3. Distribution and antibiotic resistance of pathogens isolated from ventilator-associated pneumonia patients in pediatric intensive care unit [J] . Xiao-fang Cai, Ji-min Sun, Lian-sheng Bao, 世界急诊医学杂志（英文） . 2011,第002期
4. Clinical study of midazolam sequential with dexmedetomidine for agitated patients undergoing weaning to implement light sedation in intensive care unit [J] . Xing Lu, Jun Li, Tong Li, 中华创伤杂志（英文版） . 2016,第002期
5. Factors associated with low adherence to head-of-bed elevation during mechanical ventilation in Chinese intensive care units [J] . LIU Jing-tao, SONG Hai-jing, WANG Yu, 中华医学杂志（英文版） . 2013,第005期
6. Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay. [J] . Marshall J, Finn CA, Theodore AC Critical care medicine . 2008,第2期

机译：临床药剂师强制加护病房镇静方案对机械通气时间和住院时间的影响。
7. A randomized trial of protocol-directed sedation management for mechanical ventilation in an Australian intensive care unit. [J] . Bucknall TK, Manias E, Presneill JJ Critical care medicine . 2008,第5期

机译：在澳大利亚重症监护病房进行机械通气的协议指导镇静管理的随机试验。
8. Protocolized Sedation vs Usual Care in Pediatric Patients Mechanically Ventilated for Acute Respiratory Failure A Randomized Clinical Trial [J] . Curley Martha A. Q., Wypij David, Watson R. Scott, JAMA: the Journal of the American Medical Association . 2015,第4期

机译：机械通气治疗急性呼吸衰竭的小儿患者的协议镇静与常规护理的随机临床试验
9. Mining patient data from heterogeneous sources for decision making on administration of non invasive mechanical ventilation in intensive care units [C] . Garcia Maria N.Moreno, Gonzalez Felix Martin, Robledo Javier Gonzalez, International Conference on Information Fusion . 2014

机译：来自异质源的患者数据，用于在重症监护单位管理非侵入式机械通气的决策
10. The use of an interdisciplinary paired sedation and spontaneous breathing protocol to reduce duration of mechnical ventilation and reduce length of stay in a medical intensive care unit. [D] . Van Buitenen, Nancy. 2016

机译：使用跨学科的配对镇静和自发呼吸方案来减少机械通气的持续时间并减少在重症监护病房的住院时间。
11. The Effect of Sedation Protocol Using Richmond Agitation-Sedation Scale (RASS) on Some Clinical Outcomes of Mechanically Ventilated Patients in Intensive Care Units: a Randomized Clinical Trial [O] . Zahra Taran, Masoumeh Namadian, Soghrat Faghihzadeh, 2019

机译：列治文躁动镇静量表（RASS）的镇静方案对重症监护室机械通气患者某些临床结果的影响：一项随机临床试验
12. Protocol directed sedation versus non-protocol directed sedation to reduce duration of mechanical ventilation in mechanically ventilated intensive care patients (Protocol) [O] . Aitken Leanne, Bucknall Tracy, Kent Bridie, 2012

机译：方案指导镇静与非方案镇静相比，可减少机械通气重症监护患者的机械通气时间（方案）
13. Randomized Clinical Trial of the Collaborative Assessment and Management of Suicidality vs. Enhanced Care as Usual for Sucidal Soldiers. [R] . Jobes, D., Comtois, K., Gutierrez, P., 2017

机译：随机临床试验对自杀性士兵的自杀与加强护理的协作评估和管理。

Effect of a Sedation and Ventilator Liberation Protocol vs Usual Care on Duration of Invasive Mechanical Ventilation in Pediatric Intensive Care Units A Randomized Clinical Trial

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