Challenges in small-molecule target identification: a commentary on 'BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models'

Birkinshaw Richard W.

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Challenges in small-molecule target identification: a commentary on 'BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models'

机译：小分子目标识别中的挑战：“BDA-366，推定的BCL-2 BH4结构拮抗剂，在各种癌细胞模型中独立于BCL-2诱导细胞凋亡的评论”

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《Cell death and differentiation》 |2021年第3期|共3页
作者
Birkinshaw Richard W.;
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Walter &

Eliza Hall Inst Med Res 1G Royal Parade Melbourne Vic 3052 Australia;

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正文语种 eng
中图分类细胞生物学;
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1. Small interfering RNA targeting HMGN5 induces apoptosis via modulation of a mitochondrial pathway and Bcl-2 family proteins in prostate cancer cells [J] . Xiao-Yu Zhang, Zhong-Qiang Guo, Shi-Qi Ji, 亚洲男性学杂志（英文版） . 2012,第003期
2. Small interfering RNA of cyclooxygenase-2 induces growth inhibition and apoptosis independently of Bcl-2 in human myeloma RPMI8226 cells [J] . Qiu-bai LI, Zhi-chao CHEN, Yong YOU, 中国药理学报：英文版 . 2007,第007期
3. Small hairpin RNA targeting at Bcl-2 increases cytarabine-induced apoptosis in Raji cells [J] . Dongmei He, Baoying Fang 生物化学与生物物理学报：英文版 . 2009,第002期
4. BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models [J] . Tamara Vervloessem, Binu K. Sasi, Elena Xerxa, Cell death & disease. . 2020,第9期

机译：BDA-366，推定的BCL-2 BH4结构域拮抗剂，在各种癌细胞模型中独立于BCL-2诱导细胞凋亡
5. Cancer cell death strategies by targeting Bcl-2's BH4 domain [J] . de Ridder Ian, Kerkhofs Martijn, Veettil Santhini Pulikkal, Biochimica et biophysica acta. Molecular cell research . 2021,第5期

机译：靶向BCL-2的BH4结构域癌细胞死亡策略
6. Small-molecule inhibitor of Bcl-2 (TW-37) suppresses growth and enhances cisplatin-induced apoptosis in ovarian cancer cells [J] . Haixia Wang, Zhifeng Zhang, Xiuping Wei, Journal of Ovarian Research . 2015,第1期

机译：Bcl-2（TW-37）的小分子抑制剂抑制生长并增强顺铂诱导的卵巢癌细胞的细胞凋亡
7. Apoptosis Induced in Ovarian Cancer Cells by HPMA Copolymer-Bound DoxorubicinIs Mediated by Bcl-2 Family Proteins [C] . Alexander Malugin, Pavla Kopecková, Jindrich Kopecek Annual meeting exposition of the Controlled Release Society . 2005

机译：Bcl-2家族蛋白介导的HPMA共聚物结合的阿霉素诱导卵巢癌细胞凋亡。
8. Regulation of apoptosis by the Bcl-2 family of proteins in the LNCaP prostate cancer cell line progression model. [D] . Rothermund, Christy Ann. 2003

机译：LNCaP前列腺癌细胞系进展模型中Bcl-2蛋白家族对细胞凋亡的调节。
9. BDA-366 a putative Bcl-2 BH4 domain antagonist induces apoptosis independently of Bcl-2 in a variety of cancer cell models [O] . Tamara Vervloessem, Binu K. Sasi, Elena Xerxa, 2020

机译：BDA-366推定的BCL-2 BH4结构域拮抗剂在各种癌细胞模型中独立于BCL-2诱导细胞凋亡
10. Correction to: Challenges in small-molecule target identification: a commentary on “BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models” [O] . Richard W. Birkinshaw 2021

机译：纠正：小分子目标识别中的挑战：“BDA-366，推定的BCL-2 BH4结构拮抗剂，诱导细胞凋亡的评论，在各种癌细胞模型中独立地诱导细胞凋亡”
11. Regulation of Calcium Fluxes and Apoptosis by BCL-2 Family Proteins in Prostate Cancer Cells [R] . McConkey, D. J. 2007

机译：BCL-2家族蛋白对前列腺癌细胞钙通量和细胞凋亡的调节作用

Challenges in small-molecule target identification: a commentary on 'BDA-366, a putative Bcl-2 BH4 domain antagonist, induces apoptosis independently of Bcl-2 in a variety of cancer cell models'

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