Managing older adults with Ph-negative ALL: What is new? Recent advances in treating older adults with ALL

摘要

Acute lymphoblastic leukemia (ALL) among older adults continues to be associated with a dismal prognosis. Novel effective immunotherapies and targeted agents are expected to address unmet needs in adult ALL. This review has summarized recent evidence to determine whether these approaches can lead to the decreased use of chemotherapy among older adults with ALL and result in improved outcomes.