Safety of clonidine used for long-term sedation in paediatric intensive care: A systematic review

Eberl Sonja; Ahne Gabriele; Toni Irmgard; Standing Joseph; Neubert Antje

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Safety of clonidine used for long-term sedation in paediatric intensive care: A systematic review

机译：用于长期镇静的CLONIDINE在儿科重症监护下的安全性：系统评价

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Aim: Although not approved, the alpha-adrenoceptor agonist clonidine is considered an option for long-term sedation protocols in paediatric intensive care. We reviewed adverse effects of clonidine occurring in this indication.

机译：目的：尽管未经批准，α肾上腺素受体激动剂可乐定被认为是儿科重症监护中长期镇静方案的一种选择。我们回顾了可乐定在该适应症中的不良反应。

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来源
《British Journal of Clinical Pharmacology》 |2021年第3期|共21页
作者
Eberl Sonja; Ahne Gabriele; Toni Irmgard; Standing Joseph; Neubert Antje;
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作者单位

Univ Hosp Erlangen Dept Paediat &

Adolescents Med Erlangen Germany;

Univ Hosp Erlangen Dept Paediat &

Adolescents Med Erlangen Germany;

Univ Hosp Erlangen Dept Paediat &

Adolescents Med Erlangen Germany;

UCL UCL Great Ormond St Inst Child Hlth London England;

Univ Hosp Erlangen Dept Paediat &

Adolescents Med Erlangen Germany;

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原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
clonidine; critical care; paediatrics; sedation;

机译：Clonidine;关键护理;儿科;镇静;

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1. The efficacy and effectiveness of machine learning for weaning in mechanically ventilated patients at the intensive care unit: a systematic review [J] . Man Ting Kwong, Glen Wright Colopy, Anika M.Weber, 生物设计与制作(英文) . 2019,第001期
2. Quality improvement in pediatric intensive care: A systematic review of the literature [J] . Susan A.Kourtis, Jeffrey P.Burns 儿科学（英文） . 2019,第002期
3. Safety of clonidine used for long‐term sedation in paediatric intensive care: A systematic review [J] . Sonja Eberl, Gabriele Ahne, Irmgard Toni, British journal of clinical pharmacology . 2021,第3期

机译：用于长期镇静的CLONIDINE在儿科重症监护下的安全性：系统评价
4. Correction: The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial,The CLOSED trial; CLOnidine compared with midazolam for SEDation o [J] . BMJ Open . 2017,第11期

机译：更正：CLOSED试用;重症监护病房的小儿患者SED镇静使用CLOnidine与Midazolam进行比较：一项多中心随机对照试验（CLOSED试验）的研究方案;可乐定与咪达唑仑的镇静作用比较
5. The CLOSED trial; CLOnidine compared with midazolam for SEDation of paediatric patients in the intensive care unit: study protocol for a multicentre randomised controlled trial,Correction: The CLOSED trial; CLOnidine compared with midazolam for SEDation o [J] . Tuuli Metsvaht, Joost van Rosmalen, Pavla Pokorná, BMJ Open . 2017,第6期

机译：CLOSED试用;重症监护病房的小儿患者SED镇静使用CLOnidine与咪达唑仑比较：一项多中心随机对照试验的研究方案，更正：CLOSED试验;可乐定与咪达唑仑的镇静作用比较
6. Brain Monitoring of Sedation in the Intensive Care Unit Using a Recurrent Neural Network [C] . Haoqi Sun, Sunil B. Nagaraj, Oluwaseun Akeju, Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2018

机译：使用循环神经网络对重症监护室中的镇静剂进行大脑监测
7. Systematic Review of Sedation Management in the Pediatric Critical Care Unit [D] . Madelon, Myrlene. 2018

机译：儿科关键护理单位镇静管理系统综述
8. Prospective multicentre randomised double-blind equivalence study comparing clonidine and midazolam as intravenous sedative agents in critically ill children: the SLEEPS (Safety profiLe Efficacy and Equivalence in Paediatric intensive care Sedation) study. [O] . Andrew Wolf, Andrew McKay, Catherine Spowart, -1

机译：前瞻性多中心双盲等效性研究比较了可乐定和咪达唑仑作为危重症儿童静脉内镇静剂的情况：SLEEPS（小儿重症监护镇静剂的安全性有效性和等效性）研究。
9. Safety of clonidine used for long‐term sedation in paediatric intensive care: A systematic review [O] . Sonja Eberl, Gabriele Ahne, Irmgard Toni, 2020

机译：用于长期镇静的CLONIDINE的安全性：系统评价
10. Comparison of Mortality Associated with Sepsis in the Burn, Trauma, and General Intensive Care Unit Patient: A Systematic Review of the Literature. [R] . Mann, E. A., Baun, M. M., Meininger, J. C., 2012

机译：烧伤，创伤和一般重症监护病房患者脓毒症相关死亡率的比较：文献的系统评价。

Safety of clonidine used for long-term sedation in paediatric intensive care: A systematic review

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