Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

Scholz Irene; Liakoni Evangelia; Hammann Felix; Grafinger Katharina Elisabeth; Duthaler Urs; Nagler Michael; Kraehenbuhl Stephan; Haschke Manuel

首页> 外文期刊>British Journal of Clinical Pharmacology >Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

【24h】

Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

机译：金丝桃属植物（ST John's Wort）对人类赤蒿药代动力学和药效学的影响

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Aims To investigate the influence of a cytochrome P450 CYP3A4 and efflux transporter P-glycoprotein (P-gp) inducing Hypericum perforatum extract on the pharmacokinetics and pharmacodynamics of rivaroxaban.

机译：目的研究诱导贯叶连翘提取物的细胞色素P450 CYP3A4和外排转运体P-糖蛋白（P-gp）对利伐沙班药代动力学和药效学的影响。

著录项

来源
《British Journal of Clinical Pharmacology》 |2021年第3期|共9页
作者
Scholz Irene; Liakoni Evangelia; Hammann Felix; Grafinger Katharina Elisabeth; Duthaler Urs; Nagler Michael; Kraehenbuhl Stephan; Haschke Manuel;
展开▼
作者单位

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

Univ Hosp Basel Div Clin Pharmacol &

Toxicol Basel Switzerland;

Bern Univ Hosp Univ Inst Clin Chem Inselspital Bern Switzerland;

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

Univ Bern Univ Hosp Bern Dept Gen Internal Med Clin Pharmacol &

Toxicol Inselspital Bern;

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类药理学;
关键词
cytochrome P450; drug interaction; Hypericum perforatum; Pamp; 8208; glycoprotein; phenotyping; rivaroxaban; St Johnamp; apos; s wort;

机译：细胞色素p450;药物相互作用;金丝桃属植物;p＆amp;8208;糖蛋白;表术;rivaroxaban;st John＆amp;s麦汁;

相似文献

外文文献
中文文献
专利

1. Physiologically based pharmacokinetic-pharmacodynamic modeling for prediction of vonoprazan pharmacokinetics and its inhibition on gastric acid secretion following intravenous/oral administration to rats, dogs and humans [J] . Wei-min Kong, Ru-jun Xu, Ping Li, 中国药理学报：英文版 . 2020,第006期
2. Time-dependent pharmacokinetics of dexamethasone and its efficacy in human breast cancer xenograft mice: a semi-mechanism-based pharmacokinetic/pharmacodynamic model [J] . Jian LI, Rong CHEN, Qing-yu YAO, 中国药理学报：英文版 . 2018,第003期
3. Effect of St. John＇s wort extract on depressive disorder in elderly patients with unstable angina [J] . Jian Liu, Zhao-wci Mcng, Li-yu Li, 世界急诊医学杂志(英文版) . 2010,第001期
4. Pharmacokinetic-pharmacodynamic modeling of the antitumor effect of TM208 and EGFR-TKI resistance in human breast cancer xenograft mice [J] . Xi-wei JI, Shuang-min JI, Run-tao LI, 中国药理学报：英文版 . 2016,第006期
5. Effects of St. John's Wort (Hypericum perforatum) on Tacrolimus Pharmacokinetics in Healthy Volunteers. [J] . Hebert MF, Park JM, Chen YL, The Journal of Clinical Pharmacology: Official Journal of the American College of Clinical Pharmacology . 2004,第1期

机译：圣约翰草（Hypericum perforatum）对健康志愿者中他克莫司药代动力学的影响。
6. The effects of St John's wort (Hypericum perforatum) on human cytochrome P450 activity. [J] . Wang Z, Gorski JC, Hamman MA, Clinical Pharmacology and Therapeutics . 2001,第4期

机译：圣约翰草（贯叶连翘）对人类细胞色素P450活性的影响。
7. An investigation into the acute nootropic effects of Hypericum perforatum L. (St. John's Wort) in healthy human volunteers. [J] . Ellis KA, Stough C, Vitetta L, Behavioural pharmacology . 2001,第3期

机译：贯叶连翘对健康人类志愿者的急性促智作用研究。
8. Supercritical Fluid Extraction of St. John's Wort (Hypericum perforatum L.) and Marigold (Calendula officinalis L.) [C] . Cossuta D., Baffi B., Meszaros A., European Meeting on Supercritical Fluids . 2010

机译：St. John's Wort（Hardicum Perforatum L.）和万寿菊（金盏花Officinalis L.）的超临界流体提取
9. Hypericins: A family of light -activated anthraquinones in St. John's Wort (Hypericum perforatum L.) and their importance in plant /pathogen /herbivore interaction. [D] . Sirvent, Tara Michelle. 2001

机译：金丝桃素：圣约翰草（Hypericum perforatum L.）中的光活化蒽醌家族及其在植物/病原体/草食动物相互作用中的重要性。
10. Effects of circadian clock and light on melatonin concentration in Hypericum perforatum L. (St. John’s Wort) [O] . Ming-Hsiu Chung, Tzu-Shing Deng 2020

机译：昼夜节拍时钟和光对瓜毛虫L的褪黑素浓度的影响。（圣约翰麦芽汁）
11. Proapoptotic Effect of Hypericum perforatum (St. John's Wort) Extract in Human Colorectal Adenocarcinoma Cell Line HT29 [O] . Arash A. Yegani, Erman S. Istifli, Ibrahim O. Tekeli, 2020

机译：Hutermum PerforaTum（圣约翰麦芽汁）提取物的促凋亡效应在人结肠直肠腺癌细胞系HT29中
12. Effects of St. John's Wort and Vitamin E on Breast Cancer Chemotherapeutic Agents [R] . Branda, R. F. 2004

机译：圣约翰草和维生素E对乳腺癌化疗药物的影响

Effects of Hypericum perforatum (St John's wort) on the pharmacokinetics and pharmacodynamics of rivaroxaban in humans

摘要

著录项

相似文献

相关主题

期刊订阅