The predictability and constancy over time of the electroosmotic flow in microchannels is an important consideration in microfluidic devices. A common cause for alteration of the flow is the adsorption of analytes to channel walls, for example, during capillary electrophoresis of proteins. It is shown that certain experimental data, published by Towns and Regnier (Towns, J. K.; Regnier, F. E. Anal. Chem. 1992, 64, 2473-2478.), on the anomalous elution times for proteins in capillary electrophoresis can be explained using a simple model for analyte adsorption that uses a result first reported by Anderson and Idol (Anderson, J. L.; Idol, W. K. Chem. Eng. Commun. 1985, 38, 93-106.) on the electroosmotic flux in capillaries with axial variations in zeta-potential It is suggested that it might be possible to use such a model to dynamically correct for altered elution times in capillary electrophoretic devices. [References: 16]
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机译：在微流体装置中，微通道中电渗流随时间的可预测性和恒定性是重要的考虑因素。改变流量的常见原因是分析物吸附到通道壁上，例如在蛋白质的毛细管电泳过程中。结果表明，Towns and Regnier（Towns，JK; Regnier，FE Anal。Chem。1992，64，2473-2478。）发表的关于毛细管电泳中蛋白质异常洗脱时间的某些实验数据可以用一种简单的分析物吸附模型，该模型使用了Anderson和Idol（Anderson，JL; Idol，WK Chem。Eng。Commun。1985，38，93-106。）首次报道的毛细管电渗流的结果，其轴向变化呈zeta-建议使用这种模型动态校正毛细管电泳设备中洗脱时间的改变是可能的。 [参考：16]
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