Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy

Tolkach Yuri; Gevensleben Heidrun; Bundschuh Ralph; Koyun Aydan; Huber Daniela; Kehrer Christina; Hecking Thomas; Keyver-Paik Mignon-Denise; Kaiser Christina; Ahmadzadehfar Hojjat; Essler Markus; Kuhn Walther; Kristiansen Glen

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Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy

机译：乳腺癌中前列腺特异性膜抗原：综合评价表达和放射性核素治疗的案例报告

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Purpose Prostate-specific membrane antigen (PSMA), a protein product of the folate hydrolase 1 (FOLH1) gene, is gaining increasing acceptance as a target for positron emission tomography/computer tomography (PET/CT) imaging in patients with several cancer types, including breast cancer. So far, PSMA expression in breast cancer endothelia has not been sufficiently characterized.

机译：目的的前列腺特异性膜抗原（PSMA）是叶酸水解酶1（folH1）基因的蛋白质产物，在几种癌症类型的患者中，增加了作为正电子发射断层扫描/计算机断层扫描/计算机断层扫描（PET / CT）成像的验收，包括乳腺癌。到目前为止，乳腺癌内皮的PSMA表达尚未充分表征。

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《Breast cancer research and treatment.》 |2018年第3期|共9页
作者
Tolkach Yuri; Gevensleben Heidrun; Bundschuh Ralph; Koyun Aydan; Huber Daniela; Kehrer Christina; Hecking Thomas; Keyver-Paik Mignon-Denise; Kaiser Christina; Ahmadzadehfar Hojjat; Essler Markus; Kuhn Walther; Kristiansen Glen;
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作者单位

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Inst Pathol Sigmund Freud Str 25 D-53127 Bonn;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Inst Pathol Sigmund Freud Str 25 D-53127 Bonn;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Nucl Med D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Inst Pathol Sigmund Freud Str 25 D-53127 Bonn;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Nucl Med D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Nucl Med D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Dept Obstet &

Gynecol D-53127 Bonn Germany;

Univ Bonn Univ Hosp Bonn Ctr Integrated Oncol Inst Pathol Sigmund Freud Str 25 D-53127 Bonn;

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原文格式 PDF
正文语种 eng
中图分类肿瘤学;
关键词
FOLH1; PSMA; Breast cancer; PET/CT; Expression; Endothelium; Marker;

机译：folh1;psma;乳腺癌;pet / ct;表达;内皮;标记;

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2. Can palliative radiotherapy influence prostate-specific antigen response in patients with castrate-resistant prostate cancer treated with systemic therapy （chemotherapy or abiraterone）？——a report of three cases [J] . Mohan Hingorani, Sanjay Dixit, Pattu Pugazhenthi, 癌症生物学与医学：英文版 . 2015,第001期
3. Evaluation of the Prostate Imaging Reporting and Data System for Magnetic Resonance Imaging Diagnosis of Prostate Cancer in Patients with Prostate-specific Antigen ＜20 ng/ml [J] . Xuan Wang, Jian-Ye Wang, Chun-Mei Li, 中华医学杂志（英文版） . 2016,第012期
4. Fractionated evaluation of immunohistochemical hormone receptor expression enhances prognostic prediction in breast cancer patients treated with tamoxifen as adjuvant therapy [J] . Ching-hung LIN, Huang-chun LIEN, Fu-chang HU3 浙江大学学报：B卷英文版 . 2010,第001期
5. Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy [J] . Tolkach Yuri, Gevensleben Heidrun, Bundschuh Ralph, Breast cancer research and treatment. . 2018,第3期

机译：乳腺癌中的前列腺特异性膜抗原：综合评价表达和放射性核素治疗的病例报告
6. Imaging expression of prostate-specific membrane antigen and response to PSMA-targeted beta-emitting radionuclide therapies in metastatic castration-resistant prostate cancer [J] . Vlachostergios Panagiotis J., Niaz Muhammad Junaid, Skafida Myrto, The Prostate . 2021,第5期

机译：前列腺特异性膜抗原的成像表达和对抗转移阉割抗性前列腺癌中的PSMA靶向β发射的β-发射辐射核酸疗法的响应
7. Reply to Bingzhi Wang, Huan Deng, and Lan Cao's Letter to the Editor re: Hojjat Ahmadzadehfar, Markus Essler. Prostate-specific Membrane Antigen Imaging: A Game Changer in Prostate Cancer Diagnosis and Therapy Planning. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2019.02.028 Despite its Slightly Limited Specificity, Prostate-specific Membrane Antigen Imaging is Still a Game Changer in Prostate Cancer Diagnosis and Therapy Planning [J] . Ahmadzadehfar Hojjat, Essler Markus European urology . 2019,第5期

机译：回复Bingzhi Wang，Huan Deng和Lan Cao的信到编辑Re：Hojjat Ahmadzadehfar，Markus Essler。前列腺特异性膜抗原成像：前列腺癌诊断和治疗计划中的游戏变化。 EUR UROL。在新闻。 https://doi.org/10.1016/j.eururo.2019.02.028尽管其特异性略有限制，但前列腺特异性膜抗原成像仍然是前列腺癌诊断和治疗计划中的游戏变化
8. A System Dynamics Model of Serum Prostate-Specific Antigen Screening for Prostate Cancer [C] . Anton Palma, David W. Lounsbury, Nicolas F. Schlecht, International Conference of the System Dynamics Society . 2016

机译：前列腺癌血清前列腺特异性抗原筛选的系统动力学模型
9. Studies on human prostate-specific antigen as a tumor antigen for the immunotherapy of prostate cancer in a mouse model. [D] . Willis, Richard Allen. 2002

机译：人类前列腺特异性抗原作为一种肿瘤抗原的免疫模型在小鼠模型中的研究。
10. Targeting of prostate-specific membrane antigen for radio-ligand therapy of triple-negative breast cancer [O] . Agnieszka Morgenroth, Ebru Tinkir, Andreas T. J. Vogg, 2019

机译：前列腺特异性膜抗原靶向治疗三阴性乳腺癌的放射配体
11. Targeting of prostate-specific membrane antigen for radio-ligand therapy of triple-negative breast cancer [O] . Agnieszka Morgenroth, Ebru Tinkir, Andreas T. J. Vogg, 2019

机译：针对三重阴性乳腺癌无线电配体治疗前列腺特异性膜抗原的靶向
12. Enzymatic Activation of Peptide Prodrugs by Prostate-Specific Membrane Antigen (PSMA) as Targeted Therapy for Prostate Cancer [R] . Denmeade, S. R. 2005

机译：前列腺特异性膜抗原（psma）作为靶向治疗前列腺癌对肽前药的酶促活化

Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy

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