Deficits in bone strength, density and microarchitecture in women living with HIV: A cross-sectional HR-pQCT study

Macdonald Heather M.; Maan Evelyn J.; Berger Claudie; Dunn Rachel A.; Cote Helene C. F.; Murray Melanie C. M.; Pick Neora; Prior Jerilynn C.

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Deficits in bone strength, density and microarchitecture in women living with HIV: A cross-sectional HR-pQCT study

机译：患有艾滋病毒的妇女的骨骼强度，密度和微体系结构的缺陷：横断面的HR-PQCT研究

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Purpose: With the advent of combined antiretroviral therapy (cART), life expectancy has increased among persons living with HIV, but so too has risk for comorbidities including osteoporosis and fragility fracture. To explore whether HIV status and cART influence three-dimensional measures of BMD, bone microarchitecture and strength we aimed to compare these outcomes between women living with HIV (WLWH; n = 50; 50.4 +/- 1.2 years, 44% postmenopausal) and without HIV (controls; n = 50; 51.8 +/- 1.2 years, 52% postmenopausal).

机译：目的：随着抗逆转录病毒治疗（购物车）的出现，艾滋病毒患者的人群中的预期寿命增加，但是，对包括骨质疏松症和脆弱性骨折的合并症也有风险。探讨艾滋病毒现状和推车是否影响了BMD，骨骼微体系结构和力量的三维措施，我们旨在比较艾滋病毒（WLWH; N = 50; 50.4 +/-1.2岁，44％绝经期）和没有艾滋病毒（对照; n = 50; 51.8 +/- 1.2岁，后期52％）。

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来源
《Bone》 |2020年第1期|共10页
作者
Macdonald Heather M.; Maan Evelyn J.; Berger Claudie; Dunn Rachel A.; Cote Helene C. F.; Murray Melanie C. M.; Pick Neora; Prior Jerilynn C.;
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作者单位

Univ British Columbia Fac Med Dept Family Practice 59-50 Univ Blvd Vancouver BC V6T 1Z3 Canada;

BC Womens Hosp &

Hlth Ctr Oak Tree Clin 4500 Oak St Vancouver BC V5Z 0A7 Canada;

McGill Univ Res Inst Hlth Ctr 2155 Guy St Suite 500 Montreal PQ H3H 2R9 Canada;

Univ British Columbia Dept Pathol &

Lab Med Rm G227 2211 Wesbrook Mall Vancouver BC V6T 2B5;

Womens Hlth Res Inst H214-4500 Oak Vancouver BC V6H 3N1 Canada;

BC Womens Hosp &

Hlth Ctr Oak Tree Clin 4500 Oak St Vancouver BC V5Z 0A7 Canada;

BC Womens Hosp &

Hlth Ctr Oak Tree Clin 4500 Oak St Vancouver BC V5Z 0A7 Canada;

Womens Hlth Res Inst H214-4500 Oak Vancouver BC V6H 3N1 Canada;

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原文格式 PDF
正文语种 eng
中图分类骨科学（运动系疾病、矫形外科学）;
关键词
Human immunodeficiency virus; Bone strength; HR-pQCT; Women; Areal bone mineral density;

机译：人类免疫缺陷病毒;骨骼强度;HR-PQCT;女性;面积骨矿物密度;

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Deficits in bone strength, density and microarchitecture in women living with HIV: A cross-sectional HR-pQCT study

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