A Cartridge System for Organometallic Catalysis:Sequential Catalysis and Separation Using Supercritical Carbon Dioxide to Switch Phases

摘要

There is continued interest in homogeneous organometallic catalysis as an important synthetic tool in the research and production of fine chemicals and Pharmaceuticals.As a consequence,effective separation techniques are needed increasingly for the clean isolation of products and catalyst recycling.A promising approach toward this goal is provided by regulated systems in which a defined substitution pattern in the periphery of the metal's coordination sphere affects the catalyst's solubility,making it possible to switch between two states:the catalyst is homogeneously dissolved during the reaction and precipitates quantitatively in the seoaration staee.