Hierarchically Structured Microparticles Formed by Interfacial Instabilities of Emulsion Droplets Containing Amphiphilic Block Copolymers

摘要

The extraction of organic solvent from oil-in-water emulsions is a simple and widely-used technique to prepare polymeric microparticles and microcapsules for drug delivery applications.Typically,a hydrophobic polymer is first dissolved in an organic solvent that is immiscible or slightly miscible with water;this solution is then emulsified with water and suitable stabilizers to form a single or double emulsion.