Calculation by GAMOS/Geant4 simulation of cellular energy distributions from alpha and lithium-7 particles created by BNCT

摘要

Abstract Monte Carlo (MC) has demonstrated to be a suitable technique to evaluate the microdosimetric parameters at the cellular level for Boron Neutron Capture Therapy (BNCT). The objectives of the current study are first to validate GAMOS MC codes with different Geant4 physics models for the range calculations of alpha particles. Once the proper physics is selected, the second objective is to determine the distributions of deposited energy in cellular medium originated by alpha and lithium-7 particles induced by 10 B(n,α) 7 Li. Highlights ? GAMOS codes with different Geant4 physics models are studied for the range calculations of alpha particles. ? Alpha and lithium-7 particles produced by BNCT are studied. ? The distributions of deposited energy in cellular medium originated by 10 B(n,α) 7 Li are proposed.