A novel vapor-phase catalytic synthetic approach for industrial production of 1,1,1,3,3,3-hexafluoroisopropyl methylether

摘要

1,1,1,3,3,3-Hexafluoroisopropylmethyl ether (HFE-356mmz) is an important substitute for chlorofluorocarbons and hydrochlorofluorocarbons due to its zero ozone depletion potential and low global warming potential. However, mass production of HFE-356mmz remains a long-standing challenge. Herein, we applied metal fluorides as catalysts in the methylation of 1,1,1,3,3,3-hexafluoroisopropanol to produce HFE-356mmz for the first time.