New 'naked-eye' colori/fluorimetric 'turn-on' chemosensor: Ultrafast and ultrasensitive detection of hydrazine in similar to 100% aqueous solution and its bio-imaging in living cells

摘要

A new oligothiophene derivative (3TY) was synthesized, and used as a highly selective hydrazine (N2H4) chemosensor in similar to 100% aqueous solution with "naked-eye" colorimetric and "turn-on" fluorimetric response. This chemosensor 3TY enabled ultrafast and ultrasensitive detection of hydrazine with ultralow detection limit of 1.45 nM (0.04 ppb) in a wide sensing pH range from 6 to 10. The sensing mechanism of 3TY toward hydrazine was strongly and fully confirmed. More importantly, colorimetric paper test strip and solid support silica are easily prepared by 3TY for on-site and real-time detection of hydrazine. Furthermore, 3TY displays many potential applications for detecting N2H4 in environmental water and human urine along with bio-imaging in living HeLa cells. (C) 2020 Elsevier B.V. All rights reserved.