Direct Readout of Protein-Protein Interactions by Mass Spectrometry from Protein-DNA Microarrays

摘要

Microarray technology allows the analysis of a large number of different parameters simultaneously by using a variety of readout systems based on fluorescence,chemiluminescence,electrochemistry,radioactivity,or mass Spectrometry(MS).Of these readout systems mass Spectrometry is unique,since it provides information on an intrinsic physical parameter of the analyte,its molecular weight.