Palladium-Catalyzed Carbonylative Cyclization Cascades with Iododienes and -trienes

摘要

We report here on a novel palladium-catalyzed cyclization cascade proceeding by carbonylation of ω-iododicnes and -trienes. In this cascade, multiple carbon carbon bonds are formed by acylpalladalion cyclizalion, with incorporation of CO in each cyclizution step. The use of CO as a one-carbon unit enables (he novel cycli/alion cascade with an angular mode of ring fusion (Scheme 1).