The Consequences of Maternal-Embryonic Cross Talk During the Periconception Period on Subsequent Embryonic Development

摘要

The periconception period comprises the final maturation of sperm and the processes of fertilization and early embryonic development, which take place in the oviduct. The final goal of these important events is to lead to establishment of pregnancy leading to the birth of healthy offspring. Studies in rodents and domestic animals have demonstrated that environmental conditions experienced during early development affect critical aspects of future growth, metabolism, gene expression, and physiology. Similarly, in vitro culture of embryos can be associated with changes in fetal growth, gene expression and regulation, and postnatal behavior.