Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

Dobinson Hazel C.; Gibani Malick M.; Jones Claire; Thomaides-Brears Helena B.; Voysey Merryn; Darton Thomas C.; Waddington Claire S.; Campbell Danielle; Milligan Iain; Zhou Liqing; Shrestha Sonu; Kerridge Simon A.; Peters Anna; Stevens Zoe; Podda Audino; Martin Laura B.; DAlessio Flavia; Duy Pham Thanh; Basnyat Buddha; Baker Stephen; Angus Brian; Levine Myron M.; Blohmke Christoph J.; Pollard Andrew J.

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Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

机译：对第一个副族治疗人体挑战模型中沙门氏菌寄生虫感染的临床和微生物反应的评价

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Background. To expedite the evaluation of vaccines against paratyphoid fever, we aimed to develop the first human challenge model of Salmonella enterica serovar Paratyphi A infection.

机译：背景。为了加快对副伤寒的评价疫苗，我们旨在开发沙门氏菌肠道甲伐氏菌感染的第一个人类挑战模型。

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来源
《Clinical infectious diseases》 |2017年第8期|共8页
作者
Dobinson Hazel C.; Gibani Malick M.; Jones Claire; Thomaides-Brears Helena B.; Voysey Merryn; Darton Thomas C.; Waddington Claire S.; Campbell Danielle; Milligan Iain; Zhou Liqing; Shrestha Sonu; Kerridge Simon A.; Peters Anna; Stevens Zoe; Podda Audino; Martin Laura B.; DAlessio Flavia; Duy Pham Thanh; Basnyat Buddha; Baker Stephen; Angus Brian; Levine Myron M.; Blohmke Christoph J.; Pollard Andrew J.;
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作者单位

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

GSK Vaccines Inst Global Hlth Siena Italy;

GSK Vaccines Inst Global Hlth Siena Italy;

European Vaccine Initiat Heidelberg Germany;

Univ Oxford Hosp Trop Dis Wellcome Trust Major Overseas Programme Clin Res Unit Ho Chi Minh;

Univ Oxford Patan Acad Hlth Sci Clin Res Unit Kathmandu Nepal;

Univ Oxford Hosp Trop Dis Wellcome Trust Major Overseas Programme Clin Res Unit Ho Chi Minh;

Univ Oxford Nuffield Dept Med Oxford England;

Univ Maryland Sch Med Ctr Vaccine Dev Baltimore MD 21201 USA;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

Univ Oxford Dept Paediat Oxford Vaccine Grp Oxford England;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
paratyphoid infection; enteric fever; Salmonella enterica paratyphi A; human challenge study; immune responses;

机译：甲状腺物质感染;肠道发烧;沙门氏菌肠道帕拉替米夫A;人类挑战研究;免疫应答;

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专利

1. Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model [J] . Dobinson Hazel C., Gibani Malick M., Jones Claire, Clinical infectious diseases . 2017,第8期

机译：对第一个副族治疗人体挑战模型中沙门氏菌寄生虫感染的临床和微生物反应的评价
2. Evaluation of Bactericidal Action of Serum Collected from Paratyphoid Patients and Normal Human against Salmonella Paratyphi [J] . Md. Chhanaur Rabbee, Mohammad Shahriar, Mohiuddin Ahmed Bhuyian, Dhaka University Journal of Pharmaceutical Sciences . 2013,第1期

机译：副伤寒患者和正常人血清对副伤寒沙门氏菌的杀菌作用评价
3. Molecular and Cellular Characterization of a Salmonella enterica Serovar Paratyphi A Outbreak Strain and the Human Immune Response to Infection [J] . Ohad Gal-Mor, Jotham Suez, Dana Elhadad, Clinical and vaccine immunology: CVI . 2012,第2期

机译：沙门氏菌沙门氏菌副伤寒A暴发株的分子和细胞表征和人类对感染的免疫反应。
4. Evaluation of cross-protection afforded by a Salmonella choleraesuis vaccine against Salmonella infections in pigs under field conditions [C] . D. Maes, K. Gibson, E. Trigd, Annual Meeting of the American Association of Swine Veterinarians . 2002

机译：在现场条件下评估沙门氏菌霍乱症患者患有沙门氏菌疫苗的交叉保护
5. Evaluating the role of dendritic cells in host immune response during human T cell leukemia virus type 1 (HTLV-1) infection using a transgenic mouse model system [D] . Rahman, Saifur 2010

机译：使用转基因小鼠模型系统评估树突状细胞在人T细胞白血病病毒1型（HTLV-1）感染期间宿主免疫反应中的作用
6. Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model [O] . Hazel C. Dobinson, Malick M. Gibani, Claire Jones, -1

机译：在第一个副伤寒人类挑战模型中对副伤寒沙门氏菌A感染的临床和微生物反应的评估
7. Evaluation of the clinical and microbiological response to Salmonella Paratyphi A infection in the first paratyphoid human challenge model. [O] . Dobinson H.C., Gibani M.M., Jones C., 2017

机译：评估第一个副伤寒人类攻击模型中对甲型副伤寒沙门氏菌感染的临床和微生物反应。

Evaluation of the Clinical and Microbiological Response to Salmonella Paratyphi A Infection in the First Paratyphoid Human Challenge Model

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