Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial

Cordero Elisa; Roca-Oporto Cristina; Bulnes-Ramos Angel; Aydillo Teresa; Gavalda Joan; Moreno Asuncion; Torre-Cisneros Julian; Montejo Jose Miguel; Fortun Jesus; Munoz Patricia; Sabe Nuria; Farinas Maria Carmen; Blanes-Julia Marino; Lopez-Medrano Francisco; Suarez-Benjumea Alejandro; Martinez-Atienza Juliana; Rosso-Fernandez Clara; Perez-Romero Pilar

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Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial

机译：两剂灭活的流感疫苗改善固体器官移植受者的免疫应答：体变形1-2的结果，随机对照临床试验

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Background. Influenza vaccine effectiveness is not optimal in solid organ transplant recipients (SOTR). We hypothesized that a booster dose might increase it.

机译：背景。固体器官移植受试者（SOTR）中流感疫苗效果是不适的。我们假设增强剂量可能会增加它。

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来源
《Clinical infectious diseases》 |2017年第7期|共10页
作者
Cordero Elisa; Roca-Oporto Cristina; Bulnes-Ramos Angel; Aydillo Teresa; Gavalda Joan; Moreno Asuncion; Torre-Cisneros Julian; Montejo Jose Miguel; Fortun Jesus; Munoz Patricia; Sabe Nuria; Farinas Maria Carmen; Blanes-Julia Marino; Lopez-Medrano Francisco; Suarez-Benjumea Alejandro; Martinez-Atienza Juliana; Rosso-Fernandez Clara; Perez-Romero Pilar;
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作者单位

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Vall DHebron Univ Hosp Barcelona Spain;

Univ Clin Hosp Barcelona Spain;

Univ Cordoba Reina Sofia Univ Hosp Maimonides Biomed Res Inst Cordoba Cordoba Spain;

Cruces Univ Hosp Bizkaia Spain;

Univ Hosp Ramon &

Cajal Madrid Spain;

Univ Hosp Gregorio Maranon Inst Invest Sanitaria Hosp Gregorio Maranon CIBER Enfermedades;

Univ Hosp Bellvitge Reg Infect Dis Grp Hosp Lobregat Barcelona Spain;

Univ Hosp Marques Valdecilla Santander Spain;

Univ Hosp La Fe Valencia Spain;

Univ Hosp 12 Octubre Inst Invest Biomed I 12 Madrid Spain;

Univ Hosp Virgen Macarena Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

Univ Seville Univ Hosp Virgen Racio CSIC Inst Biomed Seville Clin Unit Infect Dis Seville Spain;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
influenza vaccine; immune response; solid organ transplantation; booster dose;

机译：流感疫苗;免疫应答;固体器官移植;增强剂量;

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专利

1. Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial [J] . Cordero Elisa, Roca-Oporto Cristina, Bulnes-Ramos Angel, Clinical infectious diseases . 2017,第7期

机译：两剂灭活的流感疫苗改善固体器官移植受者的免疫应答：体变形1-2的结果，随机对照临床试验
2. Immunogenicity and safety of double versus standard dose of the seasonal influenza vaccine in solid-organ transplant recipients: A randomized controlled trial [J] . Mombelli Matteo, Rettby Nils, Perreau Matthieu, Vaccine . 2018,第41期

机译：固体器官移植受者的季节性流感疫苗的双重与标准剂量的免疫原性和安全性：随机对照试验
3. Cell-Mediated Immune Responses After Influenza Vaccination of Solid Organ Transplant Recipients: Secondary Outcomes Analyses of a Randomized Controlled Trial [J] . The Journal of Infectious Diseases . 2020,第1期

机译：细胞介导的免疫因子疫苗接种固体器官移植受者的免疫应答：随机对照试验的二次结果分析
4. A randomized controlled clinical trial to evaluate the effect of an intranasal respiratory vaccine on calf health, ultrasonographic lung consolidation, and growth in Holstein dairy calves [C] . T. L. Ollivett, K. E. Leslie, T. Duffield, Annual Conference of the American^Association^of^Bovine^Practitioners., Conference . 2014

机译：一种随机对照临床试验，评价鼻内呼吸疫苗对荷斯坦乳制牛犊牛犊健康，超声肺固结和生长的影响
5. The effect of maintaining high hemoglobin levels on long-term kidney function in kidney transplant recipients: a randomized controlled trial [D] . Tsujita Makoto, 辻田誠 2019

机译：维持高血红蛋白水平对肾移植受者长期肾脏功能的影响：一项随机对照试验
6. Efficacy and safety of a booster dose of influenza vaccination in solid organ transplant recipients TRANSGRIPE 1-2: study protocol for a multicenter randomized controlled clinical trial [O] . Juliana Martinez-Atienza, Clara Rosso-Fernández, Cristina Roca, 2014

机译：固体器官移植接受者加强剂量的流感疫苗接种的功效和安全性TRANSGRIPE 1-2：一项多中心随机对照临床试验的研究方案
7. Efficacy and safety of a booster dose of influenza vaccination in solid organ transplant recipients, TRANSGRIPE 1-2: study protocol for a multicenter, randomized, controlled clinical trial [O] . Martínez-Atienza Juliana, Rosso-Fernández Clara, Roca Cristina, 2015

机译：实体器官移植接受者加强剂量的流感疫苗接种的有效性和安全性，TRANSGRIPE 1-2：一项多中心，随机，对照临床试验的研究方案
8. High Dose Atorvastatin Decreases Cellular Markers of Immune Activation Without Affecting HIV-1 RNA Levels: Results of a Double-Blind Randomized Placebo Controlled Clinical Trial [R] . Ganesan, A., Crum-Cianflone, N., Higgins, J., 2011

机译：高剂量阿托伐他汀减少免疫激活的细胞标记而不影响HIV-1 RNa水平：双盲随机安慰剂对照临床试验的结果

Two Doses of Inactivated Influenza Vaccine Improve Immune Response in Solid Organ Transplant Recipients: Results of TRANSGRIPE 1-2, a Randomized Controlled Clinical Trial

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