A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages

Tripura Rupam; Peto Thomas J.; Chea Nguon; Chan Davoeung; Mukaka Mavuto; Sirithiranont Pasathorn; Dhorda Mehul; Promnarate Cholrawee; Imwong Mallika; von Seidlein Lorenz; Duanguppama Jureeporn; Patumrat Krittaya; Huy Rekol; Grobusch Martin P.; Day Nicholas P. J.; White Nicholas J.; Dondorp Arjen M.

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A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages

机译：大规模药物管理对受控试验中断柬埔寨村疟原虫中断抗性抗性疟疾疟疾

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Background. The increase in multidrug-resistant Plasmodium falciparum in Southeast Asia suggests a need for acceleration of malaria elimination. We evaluated the effectiveness and safety of mass drug administration (MDA) to interrupt malaria transmission.

机译：背景。东南亚耐多种抗性疟原虫的增加表明需要加速疟疾消除。我们评估了大规模药物管理局（MDA）的有效性和安全性，以中断疟疾传播。

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来源
《Clinical infectious diseases》 |2018年第6期|共10页
作者
Tripura Rupam; Peto Thomas J.; Chea Nguon; Chan Davoeung; Mukaka Mavuto; Sirithiranont Pasathorn; Dhorda Mehul; Promnarate Cholrawee; Imwong Mallika; von Seidlein Lorenz; Duanguppama Jureeporn; Patumrat Krittaya; Huy Rekol; Grobusch Martin P.; Day Nicholas P. J.; White Nicholas J.; Dondorp Arjen M.;
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作者单位

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Natl Ctr Parasitol Entomol &

Malaria Control Phnom Penh Cambodia;

Prov Hlth Dept Battambang Cambodia;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

World Wide Antimalarial Resistance Network Oxford England;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Dept Mol Trop Med &

Genet Bangkok Thailand;

Mahidol Univ Fac Trop Med Dept Mol Trop Med &

Genet Bangkok Thailand;

Natl Ctr Parasitol Entomol &

Malaria Control Phnom Penh Cambodia;

Univ Amsterdam Acad Med Ctr Dept Infect Dis Ctr Trop Med &

Travel Med Amsterdam Netherlands;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

Mahidol Univ Fac Trop Med Mahidol Oxford Trop Med Res Unit Bangkok Thailand;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
subclinical malaria; dihydroartemisinin-piperaquine; malaria elimination; mass drug administration; Southeast Asia;

机译：亚临床疟疾;二氢氨基氨苄蛋白 - 哌啶;疟疾消除;大众药物管理局;东南亚;

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专利

1. A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages [J] . Tripura Rupam, Peto Thomas J., Chea Nguon, Clinical infectious diseases . 2018,第6期

机译：大规模药物管理对受控试验中断柬埔寨村疟原虫中断抗性抗性疟疾疟疾
2. A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania [J] . Seif A Shekalaghe, Chris Drakeley, Sven van den Bosch, Malaria Journal . 2011,第S1期

机译：在坦桑尼亚的低流行地区，采用配用杀细胞杀伤性药物组合来阻断疟疾传播的大规模药物管理的集群随机试验
3. Effectiveness of reactive focal mass drug administration and reactive focal vector control to reduce malaria transmission in the low malaria-endemic setting of Namibia: a cluster-randomised controlled, open-label, two-by-two factorial design trial [J] . The Lancet . 2020,第10233期

机译：反应性焦油群药物施用的有效性和活性局灶性载体对纳米比亚低疟疾 - 特内射击中疟疾传播的影响：簇随机控制，开放标签，双两个因子设计试验
4. Diagnostics to support malaria elimination: Choosing an appropriate biomarker to target the subclinical Plasmodium falciparum transmission reservoir [C] . Hawkins K., Burton R., LaBarre P. IEEE Global Humanitarian Technology Conference . 2014

机译：支持消除疟疾的诊断：选择合适的生物标记物靶向亚临床恶性疟原虫传播库
5. Ivermectin mass drug administration to humans for malaria parasite transmission control. [D] . Kobylinski, Kevin. 2011

机译：伊维菌素对人类的大规模药物管理，用于控制疟原虫的传播。
6. A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages [O] . Rupam Tripura, Thomas J Peto, Nguon Chea, -1

机译：一项大规模药物管理的对照试验以中断柬埔寨村庄多药耐药恶性疟疾的传播
7. A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages [O] . Rupam Tripura, Thomas J Peto, Nguon Chea, 2018

机译：柬埔寨村庄中断多药物抗性疟疾中断传播的大规模药物管理

A Controlled Trial of Mass Drug Administration to Interrupt Transmission of Multidrug-Resistant Falciparum Malaria in Cambodian Villages

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