Two Cases with Past and Family History of Febrile Convulsion Developed Seizure-like Movements during Sevoflurane Anesthesia

摘要

Febrile convulsion in children is considered to develop because, as their brain is still immature, they are hypersensitive to hyperthermia.The incidence of febrile convulsions is highest in patients aged 6 months to 3 yr and rare in patients older than 6 yr. Although the precise risk of developing epilepsy after febrile convulsions is uncertain, febrile convulsions are known to be associated with epilepsy in childhood. Epileptic subjects are particularly sensitive to the epileptogenic effect of sevoflurane; however, the degree to which history of febrile convulsions contributes to the epileptogenic effect of sevoflurane has not been determined. Here, we report the cases of two pediatric patients with a personal and family history of febrile convulsion who experienced seizure-like movements during general anesthesia.