Viral Load and Sequence Analysis Reveal the Symptom Severity, Diversity, and Transmission Clusters of Rhinovirus Infections

Ng Kim Tien; Oong Xiang Yong; Lim Sin How; Chook Jack Bee; Takebe Yutaka; Chan Yoke Fun; Chan Kok Gan; Hanafi Nik Sherina; Pang Yong Kek; Kamarulzaman Adeeba; Tee Kok Keng

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Viral Load and Sequence Analysis Reveal the Symptom Severity, Diversity, and Transmission Clusters of Rhinovirus Infections

机译：病毒载荷和序列分析显示鼻病毒感染的症状严重程度，多样性和传输簇

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Background. Rhinovirus (RV) is one of the main viral etiologic agents of acute respiratory illnesses. Despite the heightened disease burden caused by RV, the viral factors that increase the severity of RV infection, the transmission pattern, and seasonality of RV infections remain unclear.

机译：背景。鼻病毒（RV）是急性呼吸疾病的主要病毒性病因之一。尽管RV引起的疾病负担增强了，但增加了RV感染，传动模式和RV感染季节性的病毒因素仍不清楚。

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来源
《Clinical infectious diseases》 |2018年第2期|共8页
作者
Ng Kim Tien; Oong Xiang Yong; Lim Sin How; Chook Jack Bee; Takebe Yutaka; Chan Yoke Fun; Chan Kok Gan; Hanafi Nik Sherina; Pang Yong Kek; Kamarulzaman Adeeba; Tee Kok Keng;
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作者单位

Univ Malaya Fac Med Dept Med Kuala Lumpur Malaysia;

Univ Malaya Fac Med Dept Med Kuala Lumpur Malaysia;

Univ Malaya Fac Med Dept Social &

Prevent Med Kuala Lumpur Malaysia;

Sunway Univ Sunway Inst Healthcare Dev Bandar Sunway Selangor Darul Malaysia;

Univ Malaya Fac Med Dept Med Microbiol Kuala Lumpur 50603 Malaysia;

Univ Malaya Fac Med Dept Med Microbiol Kuala Lumpur 50603 Malaysia;

Univ Malaya Fac Sci Inst Biol Sci Div Genet &

Mol Biol Kuala Lumpur Malaysia;

Univ Malaya Fac Med Dept Primary Care Med Kuala Lumpur Malaysia;

Univ Malaya Fac Med Dept Med Kuala Lumpur Malaysia;

Univ Malaya Fac Med Dept Med Kuala Lumpur Malaysia;

Sunway Univ Sunway Inst Healthcare Dev Bandar Sunway Selangor Darul Malaysia;

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原文格式 PDF
正文语种 eng
中图分类传染病;
关键词
rhinovirus; acute respiratory tract infections; symptom severity; viral load; transmission clusters;

机译：鼻病毒;急性呼吸道感染;症状严重程度;病毒载荷;传输群集;

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专利

1. Viral Load and Sequence Analysis Reveal the Symptom Severity, Diversity, and Transmission Clusters of Rhinovirus Infections [J] . Ng Kim Tien, Oong Xiang Yong, Lim Sin How, Clinical infectious diseases . 2018,第2期

机译：病毒载荷和序列分析显示鼻病毒感染的症状严重程度，多样性和传输簇
2. Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge [J] . Markus J. Lehtinen, Ashley A. Hibberd, Sofia M?nnikk?, Scientific reports. . 2018,第1期

机译：鼻腔微生物群簇与实验性鼻病毒挑战中的炎症反应，病毒载荷和症状严重程度相关联
3. Epidemiological and Viral Genomic Sequence Analysis of the 2014 Ebola Outbreak Reveals Clustered Transmission [J] . Scarpino Samuel V., Iamarino Atila, Wells Chad, Clinical infectious diseases . 2015,第7期

机译：2014年埃博拉疫情的流行病学和病毒基因组序列分析揭示了聚集传播
4. Cluster analysis in assessing the interdependencies of clinical and morphological parameters of patients with mixed infections (pulmonary tuberculosis, chronic viral hepatitis, HIV infection) and heroin addiction [C] . Pigul Evgeniia Yu, Filimonova Galina F., Tokin Ivan B., 2015 International Conference "Stability and Control Processes" in Memory of V.I. Zubov . 2015

机译：聚类分析评估混合感染（肺结核，慢性病毒性肝炎，HIV感染）和海洛因成瘾患者临床和形态学参数之间的相互依赖性
5. Evaluating the severity of acute respiratory infections: Advantage of meditation over exercise; Viral and bacterial co-infection; and Reduction of Wisconsin Upper Respiratory Symptom Survey. [D] . Obasi, Chidi N. 2012

机译：评估急性呼吸道感染的严重程度：冥想胜于运动；病毒和细菌共同感染；和减少威斯康星州上呼吸道症状调查。
6. Nasal microbiota clusters associate with inflammatory response viral load and symptom severity in experimental rhinovirus challenge [O] . Markus J. Lehtinen, Ashley A. Hibberd, Sofia Männikkö, -1

机译：鼻微生物群与实验性鼻病毒攻击中的炎症反应病毒载量和症状严重程度相关
7. Nasal microbiota clusters associate with inflammatory response, viral load, and symptom severity in experimental rhinovirus challenge [O] . Markus J. Lehtinen, Ashley A. Hibberd, Sofia Männikkö, 2018

机译：鼻腔微生物群簇与实验性鼻病毒挑战中的炎症反应，病毒载荷和症状严重程度相关联

Viral Load and Sequence Analysis Reveal the Symptom Severity, Diversity, and Transmission Clusters of Rhinovirus Infections

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