Beyond the NIH Multicenter HIV Transplant Trial Experience: Outcomes of HIV plus Liver Transplant Recipients Compared to HCV plus or HIV plus /HCV plus Coinfected Recipients in the United States

摘要

Background. The effectiveness of liver transplant (LT) in human immunodeficiency virus (HIV) and HIV/hepatitis C virus (HCV) coinfected recipients in the United States is unknown. We investigated (i) the effect of HIV on US patient and allograft LT outcomes, compared to HCV+ and HIV/HCV uninfected recipients and (ii) whether LT at centers that participated in the National Institutes of Health (NIH) Solid Organ Transplantation in HIV Trial, reflecting experience and a standardized approach to patient selection, impacted outcomes.