Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor

Garcia Silva Andrea; Marti Solano Maria; Selent Jana; Loza Garcia Mabel; Castro Perez Marian

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Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor

机译：血清素5-HT2A受体激动剂功能偏差的定量及结构假设对5-HT2A受体功能选择性的验证

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来源
《Basic & clinical pharmacology & toxicology.》 |2019年第s4期|共1页
作者
Garcia Silva Andrea; Marti Solano Maria; Selent Jana; Loza Garcia Mabel; Castro Perez Marian;
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作者单位

Univ Santiago de Compostela Ctr Res Mol Med &

Chron Dis CIMUS Santiago De Compostela Spain;

Pompeu Fabra Univ Hosp Mar Med Res Inst Dept Expt &

Hlth Sci Res Programme Biomed Informat;

Pompeu Fabra Univ Hosp Mar Med Res Inst Dept Expt &

Hlth Sci Res Programme Biomed Informat;

Univ Santiago de Compostela Ctr Res Mol Med &

Chron Dis CIMUS Santiago De Compostela Spain;

Univ Santiago de Compostela Ctr Res Mol Med &

Chron Dis CIMUS Santiago De Compostela Spain;

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原文格式 PDF
正文语种 eng
中图分类药学;
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1. Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor [J] . Garcia Silva Andrea, Marti Solano Maria, Selent Jana, Basic & clinical pharmacology & toxicology. . 2019,第S1期

机译：血清素5-HT2A受体激动剂功能偏差的定量及结构假设对5-HT2A受体功能选择性的验证
2. Antagonist functional selectivity: 5-HT2A serotonin receptor antagonists differentially regulate 5-HT2A receptor protein level in vivo. [J] . Yadav PN, Kroeze WK, Farrell MS, The Journal of Pharmacology and Experimental Therapeutics: Official Publication of the American Society for Pharmacology and Experimental Therapeutics . 2011,第1期

机译：拮抗剂的功能选择性：5-HT2A血清素受体拮抗剂在体内差异调节5-HT2A受体蛋白水平。
3. Effects of the serotonin 5-HT2A/2C receptor agonist DOI and of the selective 5-HT2A or 5-HT2C receptor antagonists EMD 281014 and SB-243213, respectively, on sleep and waking in the rat. [J] . Monti JM, Jantos H European Journal of Pharmacology: An International Journal . 2006,第1a3期

机译：血清素5-HT2A / 2C受体激动剂DOI和选择性5-HT2A或5-HT2C受体拮抗剂EMD 281014和SB-243213对大鼠睡眠和苏醒的影响。
4. The Serotonin 5-HT2A Receptor Antagonist Ritanserin Induces Apoptosis in Human Colorectal Cancer and Acts in Synergy with Curcumin [C] . Ataee R., Oufkir T., Ataee A., European Congress of Pharmacology . 2012

机译：血清素5-HT2A受体拮抗剂蓖麻素诱导人结直肠癌中的凋亡，并用姜黄素的协同作用
5. Regulatory single nucleotide polymorphisms in the human 5-HT2A receptor: Functional properties and disease risks. [D] . Myers, Regina L. 2005

机译：人类5-HT2A受体中的调节性单核苷酸多态性：功能特性和疾病风险。
6. Antagonist Functional Selectivity: 5-HT2A Serotonin Receptor Antagonists Differentially Regulate 5-HT2A Receptor Protein Level In Vivo [O] . Prem N. Yadav, Wesley K. Kroeze, Martilias S. Farrell, -1

机译：拮抗剂功能选择性：5-HT2A血清素受体拮抗剂体内差异调节5-HT2A受体蛋白水平。
7. Serotonin 5-HT2A receptor expression and functionality in postmortem frontal cortex of subjects with schizophrenia: Selective biased agonism via Gαi1-proteins [O] . Aintzane García-Bea, Patricia Miranda-Azpiazu, Carolina Muguruza, 2019

机译：血清素5-HT2A受体表达和功能在患有精神分裂症的受试者的前骨前皮：通过Gαi1-蛋白选择性偏向激动

Quantification of functional bias of serotonin 5-HT2A receptor agonists and validation of structural hypotheses on functional selectivity at 5-HT2A receptor

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