Methadone is an analgesic with low addictive side effects due to its weak potency on opioid-galanin receptor heteromers

Casado Vicent; Casado-Anguera Veronica; Moreno Estefania; Cai Ning-Sheng; Quiroz Cesar; Bonifazi Alessandro; Newman Amy H.; Belcher Annabelle M.; Ferre Sergi

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Methadone is an analgesic with low addictive side effects due to its weak potency on opioid-galanin receptor heteromers

机译：美沙酮是一种镇痛药，其副作用较低，副作用由于其对阿片毒素受体异构体的弱效力

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来源
《Basic & clinical pharmacology & toxicology.》 |2019年第s4期|共2页
作者
Casado Vicent; Casado-Anguera Veronica; Moreno Estefania; Cai Ning-Sheng; Quiroz Cesar; Bonifazi Alessandro; Newman Amy H.; Belcher Annabelle M.; Ferre Sergi;
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作者单位

Univ Barcelona Dept Biochem &

Mol Biomedicine Fac Biol Barcelona Spain;

Univ Barcelona Dept Biochem &

Mol Biomedicine Fac Biol Barcelona Spain;

Univ Barcelona Dept Biochem &

Mol Biomedicine Fac Biol Barcelona Spain;

NIDA Integrat Neurobiol Sect Intramural Res Program NIH Bethesda MD 20892 USA;

NIDA Integrat Neurobiol Sect Intramural Res Program NIH Bethesda MD 20892 USA;

NIDA Med Chem Sect Intramural Res Program NIH Bethesda MD 20892 USA;

NIDA Med Chem Sect Intramural Res Program NIH Bethesda MD 20892 USA;

Univ Maryland Sch Med Dept Psychiat Div Alcohol &

Drug Abuse Baltimore MD 21201 USA;

NIDA Integrat Neurobiol Sect Intramural Res Program NIH Bethesda MD 20892 USA;

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正文语种 eng
中图分类药学;
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1. Methadone is an analgesic with low addictive side effects due to its weak potency on opioid-galanin receptor heteromers [J] . Casado Vicent, Casado-Anguera Veronica, Moreno Estefania, Basic & clinical pharmacology & toxicology. . 2019,第S4期

机译：美沙酮是一种镇痛药，其副作用较低，副作用由于其对阿片毒素受体异构体的弱效力
2. Comparison of analgesic and systemic effects of bupivacaine, methadone, or bupivacaine/methadone administered epidurally in conscious sheep [J] . DeRossi R., Jardim P. H. A., Hermeto L. C., Australian Veterinary Journal . 2015,第5期

机译：布比卡因，美沙酮或布比卡因/美沙酮硬膜外给药对镇静绵羊的镇痛和全身作用比较
3. Analgesic effects of methadone and magnesium following posterior spinal fusion for idiopathic scoliosis in adolescents: a randomized controlled trial [J] . Martin David P., Samora Walter P., Beebe Allan C., Journal of anesthesia . 2018,第5期

机译：氨基酮和镁在脊柱融合后的镇痛作用对青少年特发性脊柱沉降的作用：随机对照试验
4. Analgesic Effects of Novel Hexapeptide Analogues as Nodceptin Receptor Ligands [C] . Emilia D. Naydenova, Nikola D. Pavlov, Petar T. Todorov American Peptide Symposium . 2011

机译：新型六肽类似物作为Nodceptin受体配体的镇痛作用
5. Glycosylating enkephalins: Design, glycosylation using sugar acetates in the preparation of glycosyl amino acids for glycopeptide syntheses, binding at the opioid receptors and analgesic effects. [D] . Keyari, Charles Mambo. 2007

机译：糖基化脑啡肽：设计，使用乙酸糖进行糖基化以制备用于糖肽合成的糖基氨基酸，在阿片样物质受体上的结合和止痛作用。
6. Functional μ-Opioid-Galanin Receptor Heteromers in the Ventral Tegmental Area [O] . Estefanía Moreno, César Quiroz, William Rea, 2017

机译：腹侧被盖区中的功能性阿片类药物-丙氨酸受体异构体
7. Faculty Opinions recommendation of Opioid-galanin receptor heteromers mediate the dopaminergic effects of opioids. [O] . Roy Wise 2019

机译：阿片类毒素受体异构体的教师意见建议介导阿片类药物的多巴胺能作用。
8. Low-Pressure Gas Effects on the Potency of an Electron Beam Against Ceramic Cloth [R] . Nunes, A. C. , Russell, C. K. , Zimmerman, F. R. , 1999

机译：低压气体对陶瓷布电子束效能的影响

Methadone is an analgesic with low addictive side effects due to its weak potency on opioid-galanin receptor heteromers

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